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胚胎处置:患者和供卵受者的选择。

Embryo disposition: choices made by patients and donor oocyte recipients.

机构信息

Nashville Fertility Center, Nashville, Tennessee 37203, USA.

出版信息

Fertil Steril. 2011 Mar 1;95(3):940-3. doi: 10.1016/j.fertnstert.2010.08.002. Epub 2010 Sep 18.

DOI:10.1016/j.fertnstert.2010.08.002
PMID:20850720
Abstract

OBJECTIVE

To compare final embryo disposition between patients and donor oocyte recipients.

DESIGN

Retrospective study.

SETTING

Private infertility practice.

PATIENT(S): Patients undergoing IVF with embryo cryopreservation.

INTERVENTION(S): None.

MAIN OUTCOME MEASURE(S): Final cryopreserved embryo disposition.

RESULT(S): A total of 1,262 patients using autologous oocytes had 5,417 embryos cryopreserved. A majority either used their embryos (39%) or continued storage (35%). Of 364 patients, who did not use their remaining 1,406 embryos, 77 (21%) donated 290 embryos to other infertile couples, 41 (11%) donated 160 embryos for research, and 246 (68%) discarded 956 embryos. Concurrently, 272 donor oocyte recipients had 1,233 embryos cryopreserved. A majority either used their embryos (40%) or continued storage (23%). Of 110 recipients that did not use their remaining 455 embryos, 62 (56%) donated 280 embryos to other infertile couples, 6 (6%) donated 31 embryos for research, and 42 (38%) discarded 144 embryos.

CONCLUSION(S): In our patient population, a higher proportion of patients with infertility ultimately used or stored their cryopreserved embryos for future reproduction compared with donor oocyte recipients. However, recipients were much more likely to donate to other infertile couples and less likely to discard their remaining embryos compared with patients.

摘要

目的

比较患者和供卵受者之间的胚胎最终去向。

设计

回顾性研究。

地点

私人不孕不育诊所。

患者

接受胚胎冷冻的 IVF 患者。

干预措施

无。

主要观察指标

最终冷冻胚胎去向。

结果

共 1262 例使用自体卵的患者有 5417 枚胚胎冷冻。大多数患者选择使用(39%)或继续储存(35%)。在 364 例未使用剩余 1406 枚胚胎的患者中,77 例(21%)将 290 枚胚胎捐赠给其他不孕夫妇,41 例(11%)将 160 枚胚胎用于研究,246 例(68%)丢弃 956 枚胚胎。同时,272 例供卵受者有 1233 枚胚胎冷冻。大多数患者选择使用(40%)或继续储存(23%)。在 110 例未使用剩余 455 枚胚胎的受者中,62 例(56%)将 280 枚胚胎捐赠给其他不孕夫妇,6 例(6%)将 31 枚胚胎用于研究,42 例(38%)丢弃 144 枚胚胎。

结论

在我们的患者人群中,与供卵受者相比,更多的不孕患者最终选择使用或储存冷冻胚胎以进行未来生育。然而,与患者相比,受者更倾向于将剩余胚胎捐赠给其他不孕夫妇,而不是丢弃。

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