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儿科人群中血压的家族聚集性。

Familial aggregation of blood pressure in a paediatric population.

作者信息

Fossali E, Ruzza M L, Codega C, Di Francesco C, Iurato M, Migliaccio M C, Monti M C, Sanarico M, Sereni F

机构信息

Clinica Pediatrica II, Università degli Studi, Milan Italy.

出版信息

Acta Paediatr Scand. 1990 Dec;79(12):1213-8. doi: 10.1111/j.1651-2227.1990.tb11412.x.

DOI:10.1111/j.1651-2227.1990.tb11412.x
PMID:2085109
Abstract

Familial aggregation of blood pressure in childhood and the difference between males and females were studied in a random sample of a nursery and school-age population in Milan. Age, sex, height, weight, skinfold thicknesses and heart rate were obtained. Blood pressure was measured in accordance with the recommendations of the Task Force of Blood Pressure Control in Children. After adjusting for age, significant correlation coefficients were found between mother and son (r = 0.17 and r = 0.11), mother and daughter (r = 0.11 and r = 0.15), and father and son (r = 0.16 and r = 0.17) for systolic and diastolic pressure, respectively; the father-daughter correlations were not statistically different (r = 0.08 and r = 0.03). Multiple regression analysis underlined the difference between males and females; height was an important determinant in the males and body weight in the females. In conclusion, anthropometric measurements should be considered in evaluations of blood pressure status. Our results suggest important differences between males and females. The BP pattern of the parents also seems more important for sons, and there seems to be a lower correlation between fathers and daughters.

摘要

在米兰的一个托儿所和学龄儿童随机样本中,研究了儿童期血压的家族聚集性以及男女之间的差异。记录了年龄、性别、身高、体重、皮褶厚度和心率。血压测量遵循儿童血压控制工作组的建议。在对年龄进行校正后,发现母亲与儿子(收缩压r = 0.17,舒张压r = 0.11)、母亲与女儿(收缩压r = 0.11,舒张压r = 0.15)以及父亲与儿子(收缩压r = 0.16,舒张压r = 0.17)的收缩压和舒张压之间分别存在显著的相关系数;父亲与女儿的相关性无统计学差异(收缩压r = 0.08,舒张压r = 0.03)。多元回归分析强调了男女之间的差异;身高是男性血压的重要决定因素,而体重是女性血压的重要决定因素。总之,在评估血压状况时应考虑人体测量指标。我们的结果表明男女之间存在重要差异。父母的血压模式对儿子似乎更为重要,而父亲与女儿之间的相关性似乎较低。

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