Yale University School of Nursing, New Haven, Connecticut, USA.
Diabetes Care. 2011 Jan;34(1):193-7. doi: 10.2337/dc10-1197. Epub 2010 Sep 20.
The purpose of this study was to determine the impact of sex and race/ethnicity on metabolic risk and health behaviors in minority youth.
A total of 173 seventh graders (46% male and 54% female; 49% Hispanic and 51% African American) with BMI ≥85th percentile and a family history of diabetes were assessed with weight, height, BMI, percent body fat, and waist circumference measures. Laboratory indexes included 2-h oral glucose tolerance tests with insulin levels at 0 and 2 h, fasting A1C, and lipids. Insulin resistance was estimated by homeostasis model assessment (HOMA-IR). Youth also completed questionnaires evaluating health behaviors.
Average BMI (31.6 ± 6.4 kg/m²) and percent body fat (39.5 ± 10.6%) were high. All participants demonstrated insulin resistance with elevated HOMA-IR values (8.5 ± 5.2). Compared with African American youth, Hispanic youth had higher triglycerides and lower HDL cholesterol despite similar BMI. Hispanic youth reported lower self-efficacy for diet, less physical activity, and higher total fat intake. Male youth had higher glucose (0 and 2 h) and reported more physical activity, more healthy food choices, and higher calcium intake than female youth.
Screening high-risk youth for insulin resistance and lipid abnormalities is recommended. Promoting acceptable physical activities and healthy food choices may be especially important for Hispanic and female youth.
本研究旨在确定性别和种族/民族对少数族裔青少年代谢风险和健康行为的影响。
共有 173 名七年级学生(46%为男性,54%为女性;49%为西班牙裔,51%为非裔美国人),BMI≥第 85 百分位且有糖尿病家族史,接受体重、身高、BMI、体脂百分比和腰围测量。实验室指标包括 2 小时口服葡萄糖耐量试验,同时检测 0 小时和 2 小时的胰岛素水平、空腹 A1C 和血脂。使用稳态模型评估(HOMA-IR)来估计胰岛素抵抗。青少年还完成了评估健康行为的问卷。
平均 BMI(31.6±6.4kg/m²)和体脂百分比(39.5±10.6%)较高。所有参与者的 HOMA-IR 值均升高,表明存在胰岛素抵抗。与非裔美国青少年相比,西班牙裔青少年的甘油三酯较高,高密度脂蛋白胆固醇较低,尽管他们的 BMI 相似。西班牙裔青少年报告的饮食自我效能感较低,体力活动较少,总脂肪摄入量较高。与女性青少年相比,男性青少年的血糖(0 小时和 2 小时)较高,报告的体力活动较多,选择的健康食物较多,钙摄入量较高。
建议对高风险青少年进行胰岛素抵抗和血脂异常筛查。促进可接受的体力活动和健康的食物选择可能对西班牙裔和女性青少年尤为重要。