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六年级多种族队列中2型糖尿病的风险因素:健康研究

Risk factors for type 2 diabetes in a sixth- grade multiracial cohort: the HEALTHY study.

作者信息

Kaufman Francine R, Hirst Kathryn, Linder Barbara, Baranowski Tom, Cooper Dan M, Foster Gary D, Goldberg Linn, Harrell Joanne S, Marcus Marsha D, Treviño Roberto P

出版信息

Diabetes Care. 2009 May;32(5):953-5. doi: 10.2337/dc08-1774. Epub 2009 Feb 5.

Abstract

OBJECTIVE

HEALTHY is a 3-year middle school intervention program designed to reduce risk factors for type 2 diabetes. The prevalence of diabetes risk factors at baseline in a cohort of 6,358 sixth-grade students is reported.

RESEARCH DESIGN AND METHODS

Forty-two schools at seven U.S. sites were randomly assigned to intervention or control. Students participated in baseline data collection during fall of 2006.

RESULTS

Overall, 49.3% of children had BMI >or=85th percentile, 16.0% had fasting blood glucose >or=100 mg/dl (<1% had fasting blood glucose >or=126 mg/dl), and 6.8% had fasting insulin >or=30 microU/ml. Hispanic youth were more likely to have BMI, glucose, and insulin levels above these thresholds than blacks and whites.

CONCLUSIONS

Sixth-grade students in schools with large minority populations have high levels of risk factors for type 2 diabetes. The HEALTHY intervention was designed to modify these risk factors to reduce diabetes incidence.

摘要

目的

“健康”(HEALTHY)是一项为期3年的中学干预项目,旨在降低2型糖尿病的风险因素。报告了6358名六年级学生队列中糖尿病风险因素在基线时的患病率。

研究设计与方法

美国7个地点的42所学校被随机分配到干预组或对照组。学生们在2006年秋季参与了基线数据收集。

结果

总体而言,49.3%的儿童BMI大于或等于第85百分位数,16.0%的儿童空腹血糖大于或等于100mg/dl(空腹血糖大于或等于126mg/dl的儿童不到1%),6.8%的儿童空腹胰岛素大于或等于30微单位/毫升。西班牙裔青少年比黑人和白人更有可能使BMI、血糖和胰岛素水平高于这些阈值。

结论

少数族裔人口众多的学校中的六年级学生有较高的2型糖尿病风险因素水平。“健康”干预旨在改变这些风险因素以降低糖尿病发病率。

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