Alzheimer's Disease Center and Department of Neurology, Boston University School of Medicine, Robinson Complex, Boston, MA 02118-2526, USA.
Alzheimer Dis Assoc Disord. 2011 Jan-Mar;25(1):11-6. doi: 10.1097/WAD.0b013e3181f3e059.
This study examined factors associated with brain donation program participation among African American and White elders. By postal mail, participants were recruited from an Alzheimer's research registry (all of whom had been invited to participate in the Center's brain donation program) and asked to complete surveys assessing brain donation knowledge, trust in healthcare systems, and religiousness. African American respondents completed a cultural mistrust inventory. Demographic, brain donation status, and literacy data (as assessed by the Wide Range Achievement Test-3 Reading subtest) were compiled from the respondents' most recent registry visit. The survey response rate was 60% (n=184 White and n=49 Black respondents). Logistic regression, comparing religiousness, trust in healthcare institutions, and educational attainment, identified a single predictor (ie, religiousness) in the prediction of donation status among White respondents (P=0.008), whereas no predictors were observed for donation status among the Black respondents. Using all African American donors and nondonors from the registry (n=68), comparisons revealed Wide Range Achievement Test-3 Reading score differences for African American donors (46.8±5.9) and nondonors (42.8±8.4, P=0.02). Results suggest that increased religiousness is related to White elders' decisions not to donate, whereas lower reading ability might be related to African American participants' decisions not to donate.
本研究调查了与非裔美国人和白人老年人参与脑捐赠计划相关的因素。通过邮寄，从阿尔茨海默病研究登记处招募参与者（他们都被邀请参加该中心的脑捐赠计划），并要求他们完成评估脑捐赠知识、对医疗保健系统的信任和宗教信仰的调查。非裔美国受访者完成了文化不信任量表。从受访者最近的登记访问中汇编了人口统计学、脑捐赠状况和识字数据（由广域成就测验-3 阅读子测验评估）。调查的回复率为 60%（白人受访者 n=184，黑人受访者 n=49）。逻辑回归，比较宗教信仰、对医疗保健机构的信任和教育程度，确定了一个单一的预测因素（即宗教信仰），可以预测白人受访者的捐赠状况（P=0.008），而黑人受访者的捐赠状况则没有观察到预测因素。使用登记处的所有非裔美国捐赠者和非捐赠者（n=68）进行比较，发现非裔美国捐赠者（46.8±5.9）和非捐赠者（42.8±8.4，P=0.02）的广域成就测验-3 阅读得分存在差异。结果表明，宗教信仰的增强与白人老年人决定不捐赠有关，而阅读能力较低可能与非洲裔美国参与者决定不捐赠有关。
