Simão Andréa Name Colado, Lozovoy Marcell Alysson Batisti, Simão Tathiana Name Colado, Dichi Jane Bandeira, Matsuo Tiemi, Dichi Isaias
Departamento de Patologia, Universidade Estadual de Londrina, PR, Brazil.
Arq Bras Endocrinol Metabol. 2010 Aug;54(6):540-5. doi: 10.1590/s0004-27302010000600005.
To verify the effects of fish oil and soy on nitric oxide (NO) and blood pressure in patients with metabolic syndrome (MS).
Sixty women with MS were investigated in a parallel randomized design study. The first group maintained their usual diet; the second group received 25 g/day of soy; the third group received 3 g/day of n-3 fatty acids, and the fourth group the same amount previously cited of n-3 fatty acids and soy.
Serum nitric oxide metabolites showed significant increase after 90 days in the fish oil and soy groups. Systolic pressure reduced after 45 days of treatment with fish oil, whereas diastolic pressure decreased significantly throughout the study in the soy group.
NO increase and blood pressure reduction with fish oil or soy protein reinforce the importance of the influence of NO on blood pressure in patients with MS.
验证鱼油和大豆对代谢综合征（MS）患者一氧化氮（NO）及血压的影响。
采用平行随机设计研究对60名患有MS的女性进行调查。第一组维持其日常饮食；第二组每天摄入25克大豆；第三组每天摄入3克n-3脂肪酸，第四组摄入与第三组相同量的n-3脂肪酸及大豆。
90天后，鱼油组和大豆组的血清一氧化氮代谢产物显著增加。鱼油治疗45天后收缩压降低，而在整个研究过程中大豆组舒张压显著下降。
鱼油或大豆蛋白使NO增加及血压降低，这进一步证明了NO对MS患者血压影响的重要性。
