Department of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Fertil Steril. 2010 Dec;94(7):2923-6. doi: 10.1016/j.fertnstert.2010.05.008. Epub 2010 Jun 17.
The objective of this case-control study of 242 reproductive-age women was to determine the concentration of afamin in the serum and peritoneal fluid of women with and without endometriosis and to test afamin as a diagnostic marker of endometriosis. Afamin levels were altered significantly in the peritoneal fluid of women with endometriosis compared with disease-free controls, correlated with vitamin E levels, and are consistent with increased oxidative stress in the peritoneal cavity of women with endometriosis.
本病例对照研究纳入了 242 名育龄期女性，旨在确定患有和不患有子宫内膜异位症的女性血清和腹腔液中 afamin 的浓度，并检验 afamin 是否可作为子宫内膜异位症的诊断标志物。与无疾病对照组相比，患有子宫内膜异位症的女性腹腔液中 afamin 水平显著改变，与维生素 E 水平相关，且与子宫内膜异位症女性腹腔内氧化应激增加一致。
