Department of Research and Development, Shofu Inc., 11 Kamitakamatsu-cho, Fukuine, Higashiyama-ku, Kyoto 605-0983, Japan.
Dent Mater J. 2010 Oct;29(5):481-501. doi: 10.4012/dmj.2009-137. Epub 2010 Sep 16.
This paper reviews our recent studies on radical photopolymerization initiators, which are used in the design of light-curing dental adhesives and resin composites, by collating information of related studies from original scientific papers, reviews, and patent literature. The photopolymerization reactivities of acylphosphine oxide (APO) and bisacylphosphine oxide (BAPO) derivatives, and D,L-camphorquinone (CQ)/tertiary amine were investigated, and no significant differences in degree of conversion (DC) were found between BAPO and CQ/amine system (p>0.05). In addition, a novel 7,7-dimethyl-2,3-dioxobicyclo[2.2.1]heptane-1-carbonyldiphenyl phosphine oxide (DOHC-DPPO=CQ-APO) was synthesized and its ultraviolet and visible (UV-VIS) spectral behavior was investigated. CQ-APO possessed two maximum absorption wavelengths (λmax) at 350-500 nm [372 nm (from APO group) and 475 nm (from CQ moiety)], and CQ-APO-containing resins exhibited good photopolymerization reactivity, excellent color tone, relaxed operation time, and high mechanical strength. It was also found that a newly synthesized, water-soluble photoinitiator (APO-Na) improved adhesion to ground dentin.
本文通过整理原始科学论文、综述和专利文献中有关研究的信息，综述了我们近期在自由基光聚合引发剂方面的研究进展，这些引发剂用于光固化牙科胶粘剂和树脂复合材料的设计。酰基膦氧化物（APO）和双酰基膦氧化物（BAPO）衍生物以及 D,L-樟脑醌（CQ）/叔胺的光聚合反应性得到了研究，BAPO 和 CQ/胺体系的转化率（DC）没有显著差异（p>0.05）。此外，还合成了一种新型的 7,7-二甲基-2,3-二氧代双环[2.2.1]庚烷-1-羰基二苯基膦氧化物（DOHC-DPPO=CQ-APO），并研究了其紫外可见（UV-VIS）光谱行为。CQ-APO 在 350-500nm 处具有两个最大吸收波长（λmax）[372nm（来自 APO 基团）和 475nm（来自 CQ 部分）]，含 CQ-APO 的树脂表现出良好的光聚合反应性、优异的色调、宽松的操作时间和较高的机械强度。还发现，一种新合成的水溶性光引发剂（APO-Na）提高了对牙本质的黏附性。
