Gastroenterology Unit, G. Rummo Hospital, 82100, Benevento, Italy.
Dig Dis Sci. 2011 Apr;56(4):1188-93. doi: 10.1007/s10620-010-1419-7. Epub 2010 Sep 22.
The influence of aging on video capsule endoscopy (VCE) in obscure gastrointestinal bleeding (OGIB) has never been prospectively assessed.
To demonstrate if age is a risk factor for incomplete VCE examination in a setting of ongoing hospitalization for OGIB and if it affects the yield of VCE.
Forty-eight consecutive patients referred to our unit for obscure-overt GI bleeding from March 2007 to September 2009 were prospectively evaluated. Patients were divided into two groups according to their age: ≤65 years (group A) and >65 years (group B). The VCE completion rate and clinically significant findings were studied.
The cecum was reached in 73% of patients. There was no difference between the two groups of patients in the VCE completion rate (78% vs. 68%, P=0.4). The overall diagnostic yield was 61%. A significant difference in the diagnostic yield between group A and group B (45% vs. 75%, P=0.04) was shown. Angiodysplasia was diagnosed in 13 out of 24 (54%) patients of group B, whereas mucosal breaks, such as erosions or ulcers, accounted for over a quarter of the group A findings.
Old age is not a risk factor for incomplete VCE examination and it is associated with increased VCE yield.
衰老对不明原因胃肠道出血（OGIB）患者行胶囊内镜检查（VCE）的影响从未被前瞻性评估过。
旨在证明在 OGIB 患者持续住院的情况下，年龄是否是 VCE 检查不完整的危险因素，以及其是否会影响 VCE 的检出率。
2007 年 3 月至 2009 年 9 月，我们单位连续评估了 48 例因不明原因显性胃肠道出血而转至我院的患者。根据年龄将患者分为两组：≤65 岁（A 组）和＞65 岁（B 组）。研究 VCE 完成率和临床显著发现。
73%的患者到达盲肠。两组患者 VCE 完成率无差异（78% vs. 68%，P=0.4）。总的诊断检出率为 61%。A 组和 B 组之间的诊断检出率存在显著差异（45% vs. 75%，P=0.04）。B 组 24 例中有 13 例（54%）诊断为血管发育不良，而 A 组黏膜病变（如糜烂或溃疡）占四分之一以上。
高龄不是 VCE 检查不完整的危险因素，与 VCE 检出率增加有关。
