Triantafyllou K, Kalantzis C, Papadopoulos A A, Apostolopoulos P, Rokkas T, Kalantzis N, Ladas S D
Hepato-Gastroenterology Unit, 2nd Department of Internal Medicine, Medical School, Athens University, Attikon University General Hospital, 124 62 Haidari, Athens, Greece.
Dig Liver Dis. 2007 Jun;39(6):575-80. doi: 10.1016/j.dld.2007.01.024. Epub 2007 Apr 12.
Small intestine video-capsule endoscopy examination in patients with diabetes mellitus may be incomplete due to delayed gastric emptying.
To measure video-capsule endoscopy gastric and small bowel transit time and to assess the completeness of the examination in diabetes mellitus patients.
In this retrospective, case-control study, we examined capsule endoscopy videos from 29 consecutive diabetes mellitus patients. Fifty-eight matched for sex, type of preparation, age and reason for referral non-diabetic controls were selected from our video-capsule endoscopy database. Two independent experienced investigators measured transit times and assessed examinations' completeness.
Video-capsule endoscopy gastric transit time was significantly longer in diabetes mellitus (87, 1-478 min) compared to non-diabetic patients (24, 4-108 min, p<0.001). The caecum was visualized in 20/29 (69%) diabetes mellitus and 52/58 (89.6%) non-diabetic controls (p=0.02). In 16 diabetes mellitus patients that video-capsule endoscopy reached the caecum, small bowel transit time was significantly shorter (261.2+/-55.5 min) compared to their 32 non-diabetic matched controls (302+/-62.7 min, p=0.03).
Patients with type 2 diabetes mellitus have prolonged video-capsule endoscopy gastric transit time compared to non-diabetic patients. Prospective studies are required to complete our understanding of video-capsule endoscopy transit times in the setting of diabetes mellitus.
糖尿病患者的小肠视频胶囊内镜检查可能因胃排空延迟而不完整。
测量视频胶囊内镜的胃和小肠转运时间，并评估糖尿病患者检查的完整性。
在这项回顾性病例对照研究中，我们检查了29例连续糖尿病患者的胶囊内镜视频。从我们的视频胶囊内镜数据库中选取了58例性别、准备类型、年龄和转诊原因相匹配的非糖尿病对照。两名独立的经验丰富的研究人员测量了转运时间并评估了检查的完整性。
与非糖尿病患者（24，4 - 108分钟，p<0.001）相比，糖尿病患者的视频胶囊内镜胃转运时间明显更长（87，1 - 478分钟）。20/29（69%）的糖尿病患者和52/58（89.6%）的非糖尿病对照观察到了盲肠（p = 0.02）。在16例视频胶囊内镜到达盲肠的糖尿病患者中，小肠转运时间明显短于32例匹配的非糖尿病对照（261.2±55.5分钟对302±62.7分钟，p = 0.03）。
与非糖尿病患者相比，2型糖尿病患者的视频胶囊内镜胃转运时间延长。需要进行前瞻性研究以完善我们对糖尿病情况下视频胶囊内镜转运时间的理解。
