慢性阻塞性肺疾病及慢性肺源性心脏病中氧耗量与氧输送的关系

[Relation between oxygen consumption and oxygen delivery in chronic obstructive pulmonary diseases and chronic cor pulmonale].

作者信息

Zhang H Y, Qiu H G, Wong X Z

机构信息

Respiratory Disease Research Center, Red-Cross Chao-yang Hospital, Beijing.

出版信息

Zhonghua Nei Ke Za Zhi. 1990 Oct;29(10):597-9, 637.

PMID:2085998

Abstract

An investigation of 13 cases of COPD and 15 cases of chronic cor pulmonale caused by COPD revealed that oxygen consumption was not related to oxygen delivery in these patients. Tissue hypoxia was not so severe in stable state of COPD and remitting period of chronic cor pulmonale, although the oxygen delivery was decreased. The demand of oxygen consumption could still be met by means of compensatory mechanism in the body. Oxygen consumption was usually a little lower than normal (114.0 +/- 11.2 ml/min/M2) in COPD; while that in cor pulmonale a little higher than normal (145 +/- 32.4 ml/min/M2). There was significant difference (P less than 0.01). This could be used as one of the diagnostic criteria when combined with clinical data.

摘要

对13例慢性阻塞性肺疾病（COPD）患者及15例由COPD引起的慢性肺源性心脏病患者的调查显示，这些患者的氧耗量与氧输送无关。在COPD稳定期和慢性肺源性心脏病缓解期，尽管氧输送减少，但组织缺氧并不严重。机体可通过代偿机制满足氧耗需求。COPD患者的氧耗量通常略低于正常水平（114.0±11.2毫升/分钟/平方米）；而肺源性心脏病患者的氧耗量略高于正常水平（145±32.4毫升/分钟/平方米）。两者差异有统计学意义（P＜0.01）。结合临床资料，这可作为诊断标准之一。