Universitair Kinderziekenhuis Brussel, Belgium.
Acta Paediatr. 2011 Feb;100(2):162-6. doi: 10.1111/j.1651-2227.2010.02021.x. Epub 2010 Oct 13.
The objective of this study is to review the indications of soy infant formula (SIF). Structured review of publications is made available through standard search engines (Pubmed,…). The medical indications for SIF are limited to galactosaemia and hereditary lactase deficiency. In the treatment of cow's milk allergy, SIF is used for economic reasons, as extensive hydrolysates are expensive. SIF is dissuaded mainly because of its phytooestrogen content. Isoflavone serum levels are much higher in SIF-fed infants than in breastfed or cow milk formula-fed infants. Administration of pure isoflavones to animals causes decreased fertility, but clinically relevant adverse effects of SIF in infants are not reported.
Soy infant formula remains an option for feeding of term born infants if breastfeeding is not possible and if standard infant formula is not tolerated.
本研究的目的是回顾大豆婴儿配方(SIF)的适应证。通过标准搜索引擎(Pubmed,…)可获得对出版物的结构化审查。SIF 的医学适应证仅限于半乳糖血症和遗传性乳糖酶缺乏症。在治疗牛奶过敏时,由于广泛水解物昂贵,因此出于经济原因使用 SIF。主要是由于其植物雌激素含量,因此不建议使用 SIF。与母乳喂养或牛奶配方喂养的婴儿相比,SIF 喂养的婴儿血清异黄酮水平要高得多。给动物服用纯异黄酮会导致生育能力下降,但尚未报道 SIF 对婴儿的临床相关不良反应。
如果无法进行母乳喂养并且无法耐受标准婴儿配方,则大豆婴儿配方仍然是足月出生婴儿的喂养选择。