弯曲低纵横比微通道中粒子的差分惯性聚焦
Differential inertial focusing of particles in curved low-aspect-ratio microchannels.
作者信息
Russom Aman, Gupta Amit K, Nagrath Sunitha, Di Carlo Dino, Edd Jon F, Toner Mehmet
机构信息
BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Shriners Hospital for Children, and Harvard Medical School, Boston, MA 02114, USA.
出版信息
New J Phys. 2009 Jul 1;11:75025. doi: 10.1088/1367-2630/11/7/075025.
Abstract
Microfluidic-based manipulation of particles is of great interest due to the insight it provides into the physics of hydrodynamic forces. Here, we study a particle-size-dependent phenomenon based on differential inertial focusing that utilizes the flow characteristics of curved, low aspect ratio (channel width ≫ height), microfluidic channels. We report the emergence of two focusing points along the height of the channel (z-plane), where different sized particles are focused and ordered in evenly spaced trains at correspondingly different lateral positions within the channel cross-section. We applied the system for continuous ordering and separation of suspension particles.
摘要
基于微流体的颗粒操控因其能深入揭示流体动力的物理特性而备受关注。在此，我们研究一种基于差分惯性聚焦的粒径依赖现象，该现象利用了弯曲的、低纵横比（通道宽度≫高度）微流体通道的流动特性。我们报告了沿通道高度（z平面）出现的两个聚焦点，不同大小的颗粒在这些点处聚焦，并在通道横截面内相应不同的横向位置以均匀间隔的序列排列。我们将该系统应用于悬浮颗粒的连续排序和分离。
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