Division of Psychology, Nottingham Trent University, Burton Street, Nottingham NG1 4BU, United Kingdom.
Drug Alcohol Depend. 2011 Jan 15;113(2-3):222-8. doi: 10.1016/j.drugalcdep.2010.08.010. Epub 2010 Sep 21.
Polydrug use potentially increases the likelihood of harm. As little is known about polydrug use patterns in the general population, it is difficult to determine patterns associated with highest likelihood.
Latent class analysis was performed on nine illicit substance groups indicating past year use of cannabis, cocaine, amphetamines, ecstasy, LSD, mushrooms, amyl nitrate, tranquillisers and heroin or crack. Analyses were based on data from a large multi-stage probability sample of the population of Great Britain (n=8538) collected in 2000. Multinomial logistic regression was performed highlighting associations between classes, and demographic and mental health variables.
A three class solution best described patterns of polydrug use; wide range, moderate range, and no polydrug use. For males and young people, there was a significantly increased chance of being in the wide and moderate range polydrug use groups compared to the no polydrug use class. Hazardous drinking was more likely in the wide and moderate polydrug classes with odds ratios of 9.99 and 2.38 (respectively) compared to the no polydrug use class. Current smokers were more likely to be wide and moderate range polydrug users compared to the no polydrug use class with odds ratios of 4.53 and 5.85 respectively. A range of mental health variables were also related to class membership.
Polydrug use in Great Britain can be expressed as three distinct classes. Hazardous alcohol use and tobacco use were strongly associated with illicit polydrug use, polydrug use appeared to be significantly associated with mental health, particularly lifetime suicide attempts.
多药物使用可能会增加危害的可能性。由于对普通人群中多药物使用模式知之甚少,因此很难确定与最高可能性相关的模式。
对过去一年使用大麻、可卡因、安非他命、摇头丸、LSD、蘑菇、亚硝酸戊酯、镇静剂和海洛因或冰毒的九种非法物质组进行潜在类别分析。分析基于 2000 年在英国大样本多阶段概率人群中收集的数据(n=8538)。进行多项逻辑回归,突出类之间的关联,以及人口统计学和心理健康变量。
三类别解决方案最好地描述了多药物使用模式;广泛范围、中等范围和无多药物使用。对于男性和年轻人来说,与无多药物使用类别相比,处于广泛和中等范围多药物使用组的可能性明显增加。与无多药物使用类别相比,危险饮酒在广泛和中等多药物类别中更有可能,优势比分别为 9.99 和 2.38。与无多药物使用类别相比,当前吸烟者更有可能成为广泛和中等范围的多药物使用者,优势比分别为 4.53 和 5.85。一系列心理健康变量也与类别成员资格有关。
英国的多药物使用可以表示为三个不同的类别。危险饮酒和吸烟与非法多药物使用密切相关,多药物使用似乎与心理健康显著相关,特别是终身自杀企图。