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[慢性阻塞性肺疾病中肺动脉高压的最新进展]

[Update on pulmonary hypertension in chronic obstructive pulmonary disease].

作者信息

Onen Zeynep Pınar, Karabıyıkoğlu Gülseren

机构信息

Department of Chest Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey.

出版信息

Tuberk Toraks. 2010;58(2):202-12.

Abstract

Secondary pulmonary hypertension (PH) is a well known possible feature in patients with chronic respiratory diseases. Owing to its frequency advanced chronic obstructive pulmonary disease (COPD) is the most common cause of PH. The studies that have focused on this topic have shown that PH is frequent during sleep, exacerbations or exercise but mean pulmonary artery pressure (PAP) is usually between 20 to 35 mmHg. Limited number of patients have severe PH, which is defined as >35 or 40 mmHg. Unfortunately, there is another subset of patients whom have minimal airway obstruction with greater PAP values called as 'out of proportion'. These two groups need special interest for further evaluation diagnosis and treatment strategy.

摘要

继发性肺动脉高压(PH)是慢性呼吸系统疾病患者中一种众所周知的可能特征。由于其发生率,晚期慢性阻塞性肺疾病(COPD)是PH最常见的病因。专注于该主题的研究表明,PH在睡眠、病情加重或运动期间很常见,但平均肺动脉压(PAP)通常在20至35 mmHg之间。只有少数患者有严重的PH,定义为>35或40 mmHg。不幸的是,还有另一组患者,他们气道阻塞轻微,但PAP值较高,被称为“不成比例”。这两组患者需要特别关注,以便进行进一步评估、诊断和制定治疗策略。

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