Mercer Stephen E, Kleinerman Rebecca, Goldenberg Gary, Emanuel Patrick O
Division of Dermatopathology, Department of Dermatology, Mount Sinai Medical Center, New York, NY 10029, USA.
J Drugs Dermatol. 2010 Sep;9(9):1072-8.
As reflected in the literature, the use of dermal filler agents has increased substantially over the last decade. Consequently, these agents are more frequently encountered on histopathologic examination. A variety of dermal fillers can be readily identified histopathologically, and the accurate identification of these agents is a critical task for dermatopathologists. Furthermore, a basic understanding of the histological features of fillers has relevance to dermatologists and dermatologic surgeons. The identification of filler substances may have important diagnostic, medico-legal and medical management considerations. This concise review aims to provide a pragmatic approach to distinguishing the agents most frequently encountered in routine practice and in the literature.
正如文献中所反映的,在过去十年中,真皮填充剂的使用大幅增加。因此,在组织病理学检查中更频繁地遇到这些制剂。多种真皮填充剂可以很容易地通过组织病理学识别,准确识别这些制剂是皮肤病理学家的一项关键任务。此外,对填充剂组织学特征的基本了解对皮肤科医生和皮肤科外科医生也有意义。填充物质的识别可能涉及重要的诊断、法医学和医疗管理方面的考虑。这篇简要综述旨在提供一种实用的方法,以区分在常规实践和文献中最常遇到的制剂。