Skoczyńska Anna, Jedrejko Marta, Martynowicz Helena, Poreba Rafał, Affelska-Jercha Anna, Steinmetz-Beck Aleksandra, Turczyn Barbara, Wojakowska Anna, Jedrychowska Iwona
Katedra i Klinika Chorób Wewnetrznych, Zawodowych i Nadciśnienia Tetniczego, Akademia Medyczna, Wrocław.
Med Pr. 2010;61(4):381-91.
Cardiovascular diseases, including hypertension, are a leading cause of death in developing and developed countries. Mercury can induce hypertension and atherosclerosis in experimental animals and humans. The assessment of the effect of mercury on the occurrence of cardiovascular system disturbances in the population is an essential task. The aim of this study was to assess the association between mercury concentration in urine and the risk of fatal cardiovascular disease during ten coming years.
The study included chemical factory workers who used mercury in the chlorine production.
The mean urine concentration of mercury in 154 workers was 4.9 +/- 11.2 microg/g creatinine. The most common disease was hypertension.
The cardiovascular risk was higher in workers exposed to small or moderate mercury levels than in workers exposed to mercury vapor in high concentrations. Furthermore, the negative association was observed between mercury exposure and smoking in workers with low urinary excretion of mercury.
包括高血压在内的心血管疾病是发展中国家和发达国家的主要死因。汞可在实验动物和人类中诱发高血压和动脉粥样硬化。评估汞对人群心血管系统紊乱发生的影响是一项重要任务。本研究的目的是评估尿汞浓度与未来十年致命心血管疾病风险之间的关联。
该研究纳入了在氯气生产中使用汞的化工厂工人。
154名工人的尿汞平均浓度为4.9±11.2微克/克肌酐。最常见的疾病是高血压。
接触低或中度汞水平的工人的心血管风险高于接触高浓度汞蒸气的工人。此外，在尿汞排泄量低的工人中，观察到汞暴露与吸烟之间存在负相关。
