Lin Han-Jou, Chen Hsuan-Yi, Sheng Yu-Jane, Tsao Heng-Kwong
Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan 106, Republic of China.
Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Jun;81(6 Pt 1):061908. doi: 10.1103/PhysRevE.81.061908. Epub 2010 Jun 3.
Cooperative clusters of N parallel bonds confined to an anchoring surface by springs of stiffness ks are considered. The free energy of a cluster can be obtained from its force-displacement relation. The dissociation kinetics of the cluster can be modeled as the dissociation of an effective single bond. There is a critical force Fc beyond which the barrier for the cluster dissociation vanishes. Fc scales such as ks1/2 and Fc/N is small compared to the critical force of a single bond. The theoretical predictions of free energy landscape and cluster lifetime are supported by numerical simulations for large number of bonds. Our study suggests that experiments measuring force-displacement relations could be useful in exploring the dynamics of adhesion clusters.
考虑由刚度为ks的弹簧限制在锚固表面上的N个平行键的协作簇。簇的自由能可以从其力-位移关系中获得。簇的解离动力学可以建模为有效单键的解离。存在一个临界力Fc，超过该临界力，簇解离的势垒消失。Fc的标度如ks1/2，并且Fc/N与单键的临界力相比很小。自由能景观和簇寿命的理论预测得到了大量键的数值模拟的支持。我们的研究表明，测量力-位移关系的实验可能有助于探索粘附簇的动力学。
