Kirakosyan Zara, Saakian David B, Hu Chin-Kun
Yerevan Physics Institute, Alikhanian Brothers Street 2, Yerevan 375036, Armenia.
Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Jul;82(1 Pt 1):011904. doi: 10.1103/PhysRevE.82.011904. Epub 2010 Jul 7.
We calculate the mean fitness for evolution models, when the fitness is a function of the Hamming distance from a reference sequence, and there is a probability that this fitness is nullified (Eigen model case) or tends to the negative infinity (Crow-Kimura model case). We calculate the mean fitness of these models. The mean fitness is calculated also for the random fitnesses with logarithmic-normal distribution, reasonably describing sometimes the situation with RNA viruses.
当适应度是与参考序列的汉明距离的函数，且存在适应度被归零的概率（特征模型情况）或趋于负无穷的概率（克劳-木村模型情况）时，我们计算了进化模型的平均适应度。我们计算了这些模型的平均适应度。对于具有对数正态分布的随机适应度，我们也计算了平均适应度，这种分布有时能合理地描述RNA病毒的情况。
