Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Dermatol Ther. 2010 Sep-Oct;23(5):533-40. doi: 10.1111/j.1529-8019.2010.01356.x.
Acute genital ulcers are painful and distressing to women and perplexing to the providers who care for them. The differential diagnosis includes sexually and nonsexually transmitted infections, autoimmune conditions, drug reactions, and local manifestations of systemic illness. However, in many cases, no causative agent is identified, and lesions are classified as idiopathic aphthosis. In the setting of fever and acute onset of genital ulcers in girls and women, the term Lipschutz ulcers has been used to describe ulcers associated with an immunologic reaction to a distant source of infection or inflammation. The aims of this article are to review the differential diagnosis and pathogenesis of acute genital ulcers, to offer an evaluation and classification scheme, and to discuss treatment options for the dermatologist who cares for women and girls with vulvar ulcers.
急性生殖器溃疡会给女性带来痛苦和困扰，也会让为其提供治疗的医护人员感到困惑。鉴别诊断包括性传播和非性传播感染、自身免疫性疾病、药物反应以及全身性疾病的局部表现。然而，在许多情况下，无法确定病因，病变被归类为特发性阿弗他溃疡。在发热和女性生殖器溃疡急性发作的情况下，术语 Lipschutz 溃疡用于描述与远处感染或炎症的免疫反应相关的溃疡。本文的目的是回顾急性生殖器溃疡的鉴别诊断和发病机制，提供评估和分类方案，并讨论皮肤科医生治疗外阴溃疡女性和女孩的治疗选择。
