Division of Dermatology, University of Alberta, Edmonton, Ab, Canada.
J Cutan Med Surg. 2010 Sep-Oct;14(5):249-53. doi: 10.2310/7750.2010.09034.
The cutaneous manifestations of graft-versus-host disease (GVHD) can be classified into acute and chronic forms. Acute GVHD is defined as a skin eruption that manifests within 100 days of transplantation, whereas chronic GVHD refers to cutaneous changes that appear 100 days or more posttransplantation.
Although most chronic forms fall within lichenoid and sclerodermoid forms, there is a multitude of less common presentations. These include xerosis, follicular prominence, ichthyosis, and pityriasis rosea-like, eczematous, or psoriasiform lesions.
We report a previously unreported manifestation of chronic cutaneous GVHD, specifically calcinosis cutis universalis on a background of sclerodermoid changes.
移植物抗宿主病（GVHD）的皮肤表现可分为急性和慢性两种形式。急性 GVHD 是指移植后 100 天内出现的皮肤疹，而慢性 GVHD 是指移植后 100 天或更长时间出现的皮肤改变。
虽然大多数慢性形式属于苔藓样和硬皮病样，但也有许多不太常见的表现。这些包括干燥、毛囊突出、鱼鳞病和玫瑰糠疹样、湿疹样或银屑病样病变。
我们报告了一种以前未报道过的慢性皮肤 GVHD 表现，即在硬皮病样改变的背景下出现全身性钙沉着症。
