左心室心肌致密化不全：一种新型心力衰竭。

Left ventricular noncompaction: a new form of heart failure.

机构信息

The Heart Institute, Pediatric Cardiology, Heart Failure, Cardiomyopathy & Heart Transplant Service, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

出版信息

Heart Fail Clin. 2010 Oct;6(4):453-69, viii. doi: 10.1016/j.hfc.2010.06.005.

DOI:10.1016/j.hfc.2010.06.005

PMID:20869646

Abstract

In this article the newly classified cardiomyopathy known as left ventricular noncompaction is discussed. This genetic inherited form of heart disease has substantial risk of heart failure, stroke, metabolic derangement, arrhythmias, and sudden cardiac death. The disorder seems to occur because of an arrest of the normal process of development, and the genes identified to date seem to encode for cytoskeletal or sarcomeric proteins. These features are outlined.

摘要

本文讨论了一种新分类的心肌病，称为左心室心肌致密化不全。这种遗传性心脏病有发生心力衰竭、中风、代谢紊乱、心律失常和心源性猝死的巨大风险。这种疾病似乎是由于正常发育过程的停滞引起的，迄今为止确定的基因似乎编码细胞骨架或肌节蛋白。这些特征被概述。