Flaum Eye Institute, University of Rochester, Rochester, New York, USA.
J Cataract Refract Surg. 2010 Oct;36(10):1768-74. doi: 10.1016/j.jcrs.2010.04.039.
To assess the histopathology of anterior subcapsular cataract associated with a collagen copolymer posterior chamber phakic intraocular lens (pIOL) (Visian Implantable Collamer Lens) using light microscopy after pIOL explantation and cataract surgery.
John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
Laboratory investigation.
Pathology specimens related to explanted pIOLs were reviewed and preoperative and postoperative patient data collected. The anterior lens capsules and explanted pIOLs were examined.
Four eyes (3 patients) had pIOL explantation for low vault and anterior subcapsular cataract. The explanted pIOLs were the shorter length models (3, 12.1 mm; 1, 12.6 mm). Anterior segment optical coherence tomography (AS-OCT) confirmed the low pIOL vault before explantation in 2 eyes. Histopathology of the anterior subcapsular cataract showed fibrous metaplasia with a variable number of lens epithelial cell (LEC) layers attached to the inner surface of the anterior capsulorhexis specimens. Light microscopy of the explanted pIOLs showed no pigment on 1 lens, mild pigment deposition on 1 haptic, and pigment deposition throughout the anterior surface of 2 pIOLs.
Anterior subcapsular cataract associated with the pIOLs was caused by low vaulting (confirmed on AS-OCT) and consequent fibrous metaplasia of the anterior LECs. Surgeons should consider the possibility of anterior subcapsular cataract associated with shorter platforms when selecting a pIOL length for appropriate vault.
评估胶原共聚物后房型有晶状体眼人工晶状体（pIOL）（Visian 可植入Collamer 透镜）摘除联合白内障手术后前囊下白内障的组织病理学。
美国犹他州盐湖城犹他大学约翰 A. 莫兰眼中心。
实验室研究。
回顾与 pIOL 摘除相关的病理标本，并收集术前和术后患者数据。检查前晶状体囊和摘除的 pIOL。
4 只眼（3 例）因低拱高和前囊下白内障行 pIOL 摘除。摘除的 pIOL 为较短长度的模型（3 个，12.1mm；1 个，12.6mm）。前节光学相干断层扫描（AS-OCT）在 2 只眼中确认了 pIOL 拱高较低。前囊下白内障的组织病理学表现为纤维化生，有数量不等的晶状体上皮细胞（LEC）层附着在前囊切缘标本的内表面。摘除的 pIOL 的光镜检查显示 1 个镜片上无色素，1 个襻上有轻度色素沉着，2 个 pIOL 前表面有色素沉着。
pIOL 相关的前囊下白内障是由低拱高（AS-OCT 证实）和随后的前 LEC 纤维化生引起的。当选择适当拱高的 pIOL 长度时，外科医生应考虑与较短平台相关的前囊下白内障的可能性。
