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Role of the conformational rigidity in the design of biomimetic antimicrobial compounds.

作者信息

Ivankin Andrey, Livne Liran, Mor Amram, Caputo Gregory A, Degrado William F, Meron Mati, Lin Binhua, Gidalevitz David

机构信息

Center for Molecular Study of Condensed Soft Matter (μCoSM) and Division of Physics, BCPS Department, Illinois Institute of Technology, 3440 S Dearborn Street, Chicago, IL 60616, USA.

出版信息

Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8462-5. doi: 10.1002/anie.201003104.

DOI:10.1002/anie.201003104
PMID:20872385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4112193/
Abstract
摘要

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本文引用的文献

1
Divalent metal ion triggered activity of a synthetic antimicrobial in cardiolipin membranes.二价金属离子触发合成抗菌肽在心磷脂膜中的活性。
J Am Chem Soc. 2009 Oct 28;131(42):15102-3. doi: 10.1021/ja9067063.
2
A comparative study on the interactions of SMAP-29 with lipid monolayers.SMAP-29与脂质单层相互作用的比较研究。
Biochim Biophys Acta. 2010 May;1798(5):851-60. doi: 10.1016/j.bbamem.2009.09.017. Epub 2009 Oct 2.
3
Protegrin interaction with lipid monolayers: Grazing incidence X-ray diffraction and X-ray reflectivity study.防御素与脂质单分子层的相互作用：掠入射X射线衍射和X射线反射率研究。
Soft Matter. 2008;4(8):1665-1674. doi: 10.1039/b718295c.
4
Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides.模拟抗菌宿主防御肽的随机尼龙-3共聚物之间的构效关系。
J Am Chem Soc. 2009 Jul 22;131(28):9735-45. doi: 10.1021/ja901613g.
5
De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers.构象受限抗菌芳基酰胺折叠体的从头设计与体内活性
Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6968-73. doi: 10.1073/pnas.0811818106. Epub 2009 Apr 9.
6
Influence of lipid composition on membrane activity of antimicrobial phenylene ethynylene oligomers.脂质组成对抗菌亚苯基乙炔低聚物膜活性的影响。
J Phys Chem B. 2008 Mar 20;112(11):3495-502. doi: 10.1021/jp077487j. Epub 2008 Feb 23.
7
Mimicry of antimicrobial host-defense peptides by random copolymers.随机共聚物对抗菌宿主防御肽的模拟
J Am Chem Soc. 2007 Dec 19;129(50):15474-6. doi: 10.1021/ja077288d. Epub 2007 Nov 23.
8
Crystallinity of the double layer of cadmium arachidate films at the water surface.
Science. 1991 Jun 14;252(5012):1532-6. doi: 10.1126/science.252.5012.1532.
9
Improved antimicrobial peptides based on acyl-lysine oligomers.基于酰基赖氨酸低聚物的改良抗菌肽。
Nat Biotechnol. 2007 Jun;25(6):657-9. doi: 10.1038/nbt1309. Epub 2007 May 27.
10
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.抗菌肽和宿主防御肽作为新型抗感染治疗策略。
Nat Biotechnol. 2006 Dec;24(12):1551-7. doi: 10.1038/nbt1267.