Department of Cardiology, St Antonius Hospital, PO Box 2500, 3430 EM Nieuwegein, The Netherlands.
Europace. 2010 Dec;12(12):1739-44. doi: 10.1093/europace/euq341. Epub 2010 Sep 27.
The right ventricular outflow tract (RVOT) is used as an alternative pacing site, but its superiority to the RV apex remains to be established. This lack of proof may in part be explained by heterogeneity within the RVOT-paced group, due to poor definitions of the RVOT. The aim of the present study is to characterize the RVOT in terms of fluoroscopic and electrocardiographic parameters.
One hundred and forty-three patients who underwent pacemaker implantation with a ventricular lead in the RVOT were included. Lead position was determined by fluoroscopy. The RVOT was divided into three areas: anterior, septal, and free wall (FW). On a 12-lead electrocardiogram (ECG) during forced ventricular pacing, QRS duration, configuration, and amplitude was determined. Lead position was judged to be anterior in 52 (36%), septal in 43 (30%), and FW in 48 (34%) patients, respectively. QRS duration is not significantly different between groups. QRS axis differs significantly between pacing sites (septal 79 ± 31°, anterior 60 ± 46°, FW 47 ± 38°, P < 0.05). QRS vector in lead I and QRS morphology and vector in lead aVL differ significantly between pacing sites. Precordial transition is earlier (towards V1) in septal pacing.
This study demonstrates heterogeneity of pacing site and depolarization pattern within a cohort of patients paced form the RVOT. However, due to considerable overlap, we could not define clear cut-off point or devise flow-charts to match ECG and pacing site.
右心室流出道(RVOT)可用作替代起搏部位,但它优于 RV 心尖的优势仍有待确定。这种缺乏证据的情况部分可能是由于 RVOT 起搏组内的异质性造成的,这是由于 RVOT 的定义不佳。本研究旨在从透视和心电图参数方面对 RVOT 进行特征描述。
共纳入 143 例因心室导线植入 RVOT 而接受起搏器植入的患者。导线位置通过透视确定。RVOT 分为前、中隔和游离壁(FW)三个区域。在强制心室起搏时的 12 导联心电图(ECG)上,确定 QRS 持续时间、形态和幅度。分别有 52 例(36%)、43 例(30%)和 48 例(34%)患者的导线位置被判断为前、中隔和 FW。各组间 QRS 持续时间无显著差异。起搏部位的 QRS 轴显著不同(中隔 79 ± 31°,前壁 60 ± 46°,FW 47 ± 38°,P < 0.05)。I 导联的 QRS 向量、QRS 形态和 aVL 导联的 QRS 向量在起搏部位之间存在显著差异。中隔起搏时,心前区过渡较早(向 V1 方向)。
本研究表明,在 RVOT 起搏的患者队列中,起搏部位和去极化模式存在异质性。然而,由于存在相当大的重叠,我们无法定义明确的截止点或制定流程图来匹配 ECG 和起搏部位。