Suppr超能文献

老年病在中年糖尿病患者中发展。

Geriatric conditions develop in middle-aged adults with diabetes.

机构信息

Department of Family Medicine, University of Michigan, 300 N. Ingalls, Ann Arbor, MI 48109-2007, USA.

出版信息

J Gen Intern Med. 2011 Mar;26(3):272-9. doi: 10.1007/s11606-010-1510-y. Epub 2010 Sep 29.

Abstract

BACKGROUND

Geriatric conditions, collections of symptoms common in older adults and not necessarily associated with a specific disease, increase in prevalence with advancing age. These conditions are important contributors to the complex health status of older adults. Diabetes mellitus is known to co-occur with geriatric conditions in older adults and has been implicated in the pathogenesis of some conditions.

OBJECTIVE

To investigate the prevalence and incidence of geriatric conditions in middle-aged and older-aged adults with diabetes.

DESIGN

Secondary analysis of nationally-representative, longitudinal health interview survey data (Health and Retirement Study waves 2004 and 2006).

PARTICIPANTS

Respondents 51 years and older in 2004 (n=18,908).

MAIN MEASURES

Diabetes mellitus. Eight geriatric conditions: cognitive impairment, falls, incontinence, low body mass index, dizziness, vision impairment, hearing impairment, pain.

KEY RESULTS

Adults with diabetes, compared to those without, had increased prevalence and increased incidence of geriatric conditions across the age spectrum (p< 0.01 for each age group from 51-54 years old to 75-79 years old). Differences between adults with and without diabetes were most marked in middle-age. Diabetes was associated with the two-year cumulative incidence of acquiring new geriatric conditions (odds ratio, 95% confidence interval: 1.8, 1.6-2.0). A diabetes-age interaction was discovered: as age increased, the association of diabetes with new geriatric conditions decreased.

CONCLUSIONS

Middle-aged, as well as older-aged, adults with diabetes are at increased risk for the development of geriatric conditions, which contribute substantially to their morbidity and functional impairment. Our findings suggest that adults with diabetes should be monitored for the development of these conditions beginning at a younger age than previously thought.

摘要

背景

老年病是老年人常见的一组症状,不一定与特定疾病有关,随着年龄的增长而患病率增加。这些病症是导致老年人复杂健康状况的重要因素。已知糖尿病与老年人的老年病同时发生,并与一些病症的发病机制有关。

目的

调查患有糖尿病的中年和老年成年人中老年病的患病率和发病率。

设计

对具有全国代表性的纵向健康访谈调查数据(健康与退休研究波 2004 年和 2006 年)的二次分析。

参与者

2004 年年龄在 51 岁及以上的受访者(n=18908)。

主要测量指标

糖尿病。八项老年病:认知障碍、跌倒、尿失禁、低体重指数、头晕、视力障碍、听力障碍、疼痛。

主要结果

与没有糖尿病的成年人相比,患有糖尿病的成年人在整个年龄段内(从 51-54 岁到 75-79 岁,每个年龄组的 p<0.01)都有更高的患病率和发病率。中年时,糖尿病患者与无糖尿病患者之间的差异最为明显。糖尿病与两年内新发生老年病的累积发病率相关(优势比,95%置信区间:1.8,1.6-2.0)。发现了糖尿病-年龄的相互作用:随着年龄的增长,糖尿病与新老年病的关联减少。

结论

患有糖尿病的中年和老年成年人发生老年病的风险增加,这些病症会大大增加他们的发病率和功能障碍。我们的研究结果表明,与以前的想法相比,应从更年轻的年龄开始监测患有糖尿病的成年人是否出现这些病症。

相似文献

1
Geriatric conditions develop in middle-aged adults with diabetes.
J Gen Intern Med. 2011 Mar;26(3):272-9. doi: 10.1007/s11606-010-1510-y. Epub 2010 Sep 29.
2
Geriatric conditions and disability: the Health and Retirement Study.
Ann Intern Med. 2007 Aug 7;147(3):156-64. doi: 10.7326/0003-4819-147-3-200708070-00004.
3
Utility of Geriatric Syndrome Indicators for Predicting Subsequent Health Care Utilization in Older Adults in Taiwan.
Int J Environ Res Public Health. 2019 Feb 4;16(3):456. doi: 10.3390/ijerph16030456.
5
The co-occurrence of chronic diseases and geriatric syndromes: the health and retirement study.
J Am Geriatr Soc. 2009 Mar;57(3):511-6. doi: 10.1111/j.1532-5415.2008.02150.x. Epub 2009 Jan 23.
8
History of Incarceration and Its Association With Geriatric and Chronic Health Outcomes in Older Adulthood.
JAMA Netw Open. 2023 Jan 3;6(1):e2249785. doi: 10.1001/jamanetworkopen.2022.49785.
9
Geriatric syndromes and quality of life in older adults with diabetes.
Geriatr Gerontol Int. 2019 Jun;19(6):518-524. doi: 10.1111/ggi.13654. Epub 2019 Apr 8.

引用本文的文献

1
Associations of Age at Diagnosis and Duration of Diabetes With Morbidity and Mortality Among Older Adults.
JAMA Netw Open. 2022 Sep 1;5(9):e2232766. doi: 10.1001/jamanetworkopen.2022.32766.
2
Multimorbidity classes indicate differential patterns of health care engagement among people who inject drugs.
J Subst Abuse Treat. 2022 Nov;142:108806. doi: 10.1016/j.jsat.2022.108806. Epub 2022 May 20.
4
Frailty and geriatric conditions in older patients with idiopathic pulmonary fibrosis.
Respir Med. 2019 Mar;148:6-12. doi: 10.1016/j.rmed.2019.01.008. Epub 2019 Jan 24.
8
Preclinical models of overwhelming sepsis implicate the neural system that encodes contextual fear memory.
Mol Med. 2016 Dec;22:789-799. doi: 10.2119/molmed.2015.00201. Epub 2016 Nov 17.
10
Importance of Geriatric Syndromes in Older Patients with Diabetes with de novo Insulin Treatment: The VEGAS Study.
Drugs Real World Outcomes. 2015 Mar;2(1):73-79. doi: 10.1007/s40801-015-0014-9.

本文引用的文献

1
Diabetes mellitus and geriatric syndromes.
Geriatr Gerontol Int. 2009 Jun;9(2):105-14. doi: 10.1111/j.1447-0594.2008.00495.x.
2
The co-occurrence of chronic diseases and geriatric syndromes: the health and retirement study.
J Am Geriatr Soc. 2009 Mar;57(3):511-6. doi: 10.1111/j.1532-5415.2008.02150.x. Epub 2009 Jan 23.
3
Diabetes and the risk of multi-system aging phenotypes: a systematic review and meta-analysis.
PLoS One. 2009;4(1):e4144. doi: 10.1371/journal.pone.0004144. Epub 2009 Jan 7.
4
Geriatric conditions and disability: the Health and Retirement Study.
Ann Intern Med. 2007 Aug 7;147(3):156-64. doi: 10.7326/0003-4819-147-3-200708070-00004.
5
Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept.
J Am Geriatr Soc. 2007 May;55(5):780-91. doi: 10.1111/j.1532-5415.2007.01156.x.
6
Risk factors for falls in older disabled women with diabetes: the women's health and aging study.
J Gerontol A Biol Sci Med Sci. 2005 Dec;60(12):1539-45. doi: 10.1093/gerona/60.12.1539.
7
Setting eligibility criteria for a care-coordination benefit.
J Am Geriatr Soc. 2005 Dec;53(12):2051-9. doi: 10.1111/j.1532-5415.2005.00496.x.
8
Cerebral white matter changes and geriatric syndromes: is there a link?
J Gerontol A Biol Sci Med Sci. 2004 Aug;59(8):818-26. doi: 10.1093/gerona/59.8.m818.
9
Guidelines for improving the care of the older person with diabetes mellitus.
J Am Geriatr Soc. 2003 May;51(5 Suppl Guidelines):S265-80. doi: 10.1046/j.1532-5415.51.5s.1.x.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验