Cognitive Functions Section, Department of Rehabilitation for Sensory Functions, Research Institute of National Rehabilitation Center for Persons with Disabilities, Tokorozawa, Saitama 359-8555, Japan.
Clin Neurophysiol. 2011 May;122(5):991-6. doi: 10.1016/j.clinph.2010.08.021. Epub 2010 Sep 28.
This study evaluates the efficacy of a P300-based brain-computer interface (BCI) with green/blue flicker matrices for individuals with cervical spinal cord injury (SCI).
Ten individuals with cervical SCI (age 26-53, all male) and 10 age- and sex-matched able-bodied controls (age 27-52, all male) with no prior BCI experience were asked to input hiragana (Japanese alphabet) characters using the P300 BCI with two distinct types of visual stimuli, white/gray and green/blue, in an 8×10 flicker matrix. Both online and offline performance were evaluated.
The mean online accuracy of the SCI subjects was 88.0% for the white/gray and 90.7% for the green/blue flicker matrices. The accuracy of the control subjects was 77.3% and 86.0% for the white/gray and green/blue, respectively. There was a significant difference in online accuracy between the two types of flicker matrix. SCI subjects performed with greater accuracy than controls, but the main effect was not significant.
Individuals with cervical SCI successfully controlled the P300 BCI, and the green/blue flicker matrices were associated with significantly higher accuracy than the white/gray matrices.
The P300 BCI with the green/blue flicker matrices is effective for use not only in able-bodied subjects, but also in individuals with cervical SCI.
本研究评估了基于 P300 的脑-机接口（BCI）与绿色/蓝色闪烁矩阵在颈脊髓损伤（SCI）患者中的疗效。
10 名颈 SCI 患者（年龄 26-53 岁，均为男性）和 10 名年龄和性别匹配的健康对照组（年龄 27-52 岁，均为男性），均无 BCI 经验，使用 P300 BCI 输入平假名（日语字母）字符，视觉刺激有两种不同类型，白色/灰色和绿色/蓝色，在 8×10 的闪烁矩阵中。评估在线和离线性能。
SCI 患者的平均在线准确率为白色/灰色矩阵的 88.0%，绿色/蓝色矩阵的 90.7%。对照组的准确率分别为白色/灰色矩阵的 77.3%和绿色/蓝色矩阵的 86.0%。两种闪烁矩阵的在线准确率存在显著差异。SCI 患者的准确率高于对照组，但主效应不显著。
颈 SCI 患者成功控制了 P300 BCI，绿色/蓝色闪烁矩阵的准确率明显高于白色/灰色矩阵。
绿色/蓝色闪烁矩阵的 P300 BCI 不仅对健康受试者有效，而且对颈 SCI 患者也有效。
