Baxter M, Aly E H
Laparoscopic Colorectal Surgery and Training Unit, Aberdeen Royal Infirmary, Aberdeen, UK.
Ann R Coll Surg Engl. 2010 Oct;92(7):548-54. doi: 10.1308/003588410X12699663905311.
Dieulafoy's lesion is a relatively rare, but potentially life-threatening, condition. It accounts for 1-2% of acute gastrointestinal (GI) bleeding, but arguably is under-recognised rather than rare. Its serious nature makes it necessary to include it in the differential diagnosis of obscure GI bleeding. The aim of this study was to review the current trends in the diagnosis and management of Dieulafoy's lesion.
Using Medline, a literature search was performed for articles published in English, using the search words 'Dieulafoy'(s)' and 'gastrointestinal bleeding'. All retrieved papers were analysed and the findings are summarised in this review.
There is no consensus on the treatment of Dieulafoy's lesions. Therapeutic endoscopy can control the bleeding in 90% of patients while angiography is being accepted as a valuable alternative to endoscopy for inaccessible lesions. Currently, surgical intervention is kept for failure of therapeutic endoscopic or angiographic interventions and it should be guided by pre-operative localisation.
Advances in endoscopy have increased the detection of Dieulafoy's lesions and decreased the mortality from 80% to 8.6%. There are recent encouraging reports on the successful use of laparoscopic surgery in managing symptomatic Dieulafoy's lesions.
Dieulafoy 病是一种相对罕见但可能危及生命的疾病。它占急性胃肠道(GI)出血的 1% - 2%,但可以说它未被充分认识而非真正罕见。其严重程度使得有必要将其纳入不明原因 GI 出血的鉴别诊断中。本研究的目的是回顾 Dieulafoy 病诊断和治疗的当前趋势。
利用 Medline 数据库,以英文发表的文章为检索对象,使用检索词“Dieulafoy”(s)和“胃肠道出血”进行文献检索。对所有检索到的论文进行分析,并在本综述中总结研究结果。
对于 Dieulafoy 病的治疗尚无共识。治疗性内镜检查可控制 90%患者的出血,而血管造影术被认为是治疗难以接近病变的一种有价值的内镜替代方法。目前,手术干预仅用于治疗性内镜或血管造影干预失败的情况,且应在术前定位的指导下进行。
内镜技术的进步提高了 Dieulafoy 病的检出率,并将死亡率从 80%降至 8.6%。最近有关于成功使用腹腔镜手术治疗有症状 Dieulafoy 病的令人鼓舞的报道。