Rehabilitation/Quality of Life Special Studies Center, United States Renal Data System, Emory University, Atlanta, Georgia, USA.
Clin J Am Soc Nephrol. 2010 Nov;5(11):2040-5. doi: 10.2215/CJN.03980510. Epub 2010 Sep 30.
When patients start dialysis, their employment rate declines and disability benefits are an option. With patient sociodemographic and clinical characteristics including disability income status controlled, we investigated the significance of depressed mood and usual activity level as predictors of patients' continued employment after dialysis start.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Incident patients from 296 randomly selected dialysis clinics were surveyed in the Comprehensive Dialysis Study (CDS). Participants provided information about employment status, disability income status, education, depressive symptoms measured by the Patient Health Questionnaire-2 (PHQ-2), and usual activity level/energy expenditure measured by the Human Activity Profile. Age, gender, race, insurance, diabetes, inability to ambulate or transfer, chronic obstructive pulmonary disease, cardiovascular conditions, and hemoglobin and serum albumin values at treatment start were obtained from US Renal Data System files. Dialysis modality was defined at time of interview.
Among 585 CDS participants who worked in the previous year, 191 (32.6%) continued working after dialysis start. On the basis of the PHQ-2 cutoff score ≥3, 12.1% of patients who remained employed had possible or probable depression, compared with 32.8% of patients who were no longer employed. In adjusted analyses, higher Human Activity Profile scores were associated with increased likelihood of continued employment, and there was a borderline association between lower PHQ-2 scores and continued employment.
Screening and management of depressive symptoms and support for increased activity level may facilitate patients' opportunity for continued employment after dialysis start, along with generally improving their overall quality of life.
当患者开始透析时,他们的就业率下降,残疾福利是一种选择。在控制了患者的社会人口统计学和临床特征,包括残疾收入状况后,我们研究了抑郁情绪和日常活动水平作为预测患者透析开始后继续就业的指标的意义。
设计、地点、参与者和测量:从 296 个随机选择的透析诊所招募了综合透析研究(CDS)的病例患者。参与者提供了就业状况、残疾收入状况、教育程度、用患者健康问卷-2(PHQ-2)测量的抑郁症状,以及用人的活动概况测量的日常活动水平/能量消耗信息。年龄、性别、种族、保险、糖尿病、无法行走或转移、慢性阻塞性肺疾病、心血管状况以及治疗开始时的血红蛋白和血清白蛋白值从美国肾脏数据系统档案中获得。在访谈时定义了透析方式。
在过去一年中工作的 585 名 CDS 参与者中,有 191 人(32.6%)在开始透析后继续工作。根据 PHQ-2 截断值≥3,仍在工作的患者中有 12.1%可能或确实患有抑郁症,而不再工作的患者中有 32.8%。在调整后的分析中,较高的人类活动概况评分与继续就业的可能性增加相关,较低的 PHQ-2 评分与继续就业之间存在边缘关联。
筛查和管理抑郁症状以及支持增加活动水平可能为患者在透析开始后继续就业提供机会,并普遍提高他们的整体生活质量。