Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Section of Nephrology, Madison, Wisconsin, USA.
Clin J Am Soc Nephrol. 2011 Mar;6(3):489-96. doi: 10.2215/CJN.02550310. Epub 2011 Mar 10.
Half the individuals who reach ESRD are working age (< 65 years old) and many are at risk for job loss. Factors that contribute to job retention among working-age patients with chronic kidney disease before ESRD are unknown. The purpose of the study is to understand factors associated with maintaining employment among working-age patients with advanced kidney failure.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: In this retrospective study we reviewed the United States Renal Data System database (1992 through 2003) and selected all patients (n = 102,104) who were working age and employed 6 months before dialysis initiation. Factors that were examined for an association with maintaining employment status included demographics, comorbid conditions, ESRD cause, insurance, predialysis erythropoietin use, and dialysis modality.
Maintaining employment at the same level during the final 6 months before dialysis was more likely among (1) white men ages 30 to 49 years; (2) patients with either glomerulonephritis, cystic, or urologic causes of renal failure; (3) patients choosing peritoneal dialysis for their first treatment; (4) those with employer group or other health plans; and (5) erythropoietin usage before ESRD. Maintaining employment status was less likely among patients with congestive heart failure, cardiovascular disease, cancer, and other chronic illnesses.
The rate of unemployment in working-age patients with chronic kidney disease and ESRD is high compared with that of the general population. Treating anemia with erythropoietin before kidney failure and educating patients about work-friendly home dialysis options might improve job retention.
半数进入终末期肾病(ESRD)的患者处于工作年龄(<65 岁),许多人面临失业风险。在 ESRD 之前,导致慢性肾脏病工作年龄段患者保留工作的因素尚不清楚。本研究的目的是了解与晚期肾衰竭工作年龄段患者保持就业相关的因素。
设计、地点、参与者和测量方法:在这项回顾性研究中,我们回顾了美国肾脏数据系统数据库(1992 年至 2003 年),并选择了所有处于工作年龄且在开始透析前 6 个月有工作的患者(n=102104)。检查了与维持就业状况相关的因素包括人口统计学、合并症、ESRD 病因、保险、透析前促红细胞生成素使用情况和透析方式。
在开始透析前的最后 6 个月内,维持相同水平的就业更可能发生在:(1)年龄在 30 至 49 岁之间的白人男性;(2)肾小球肾炎、囊性或泌尿系统病因导致肾衰竭的患者;(3)选择腹膜透析作为首次治疗的患者;(4)选择雇主团体或其他健康计划的患者;(5)在 ESRD 之前使用促红细胞生成素的患者。患有充血性心力衰竭、心血管疾病、癌症和其他慢性疾病的患者维持就业的可能性较小。
与一般人群相比,慢性肾脏病和 ESRD 工作年龄段患者的失业率较高。在肾衰竭前用促红细胞生成素治疗贫血并向患者传授适合工作的家庭透析选择可能会提高工作保留率。