National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Heart Rhythm. 2011 Jan;8(1):23-8. doi: 10.1016/j.hrthm.2010.09.073. Epub 2010 Sep 29.
Indications for implantable cardioverter-defibrillator (ICD) implantation in children have expanded, yet pediatric population-based data on ICD implantation are lacking.
We characterized trends in pediatric ICD use in the United States from 1997 to 2006.
We examined national hospital administrative data from the 1997, 2000, 2003, and 2006 Kids' Inpatient Database (KID) for new ICD implants in patients younger than 18 years of age and characterized patients, hospitals, and hospitalization-related outcomes.
The number of pediatric ICD implants per year increased 3-fold (from 130 in 1997 to 396 in 2006, P = .003). Implants with a concomitant diagnosis of life-threatening arrhythmia decreased from 77% to 45% (P = .001). The average age decreased from 13.6 to 12.2 years (P = .01), and the percentage of patients younger than 5 years of age tended to increase (up to 10%, P = .09). In 2006, the number of implants per center ranged from 1 to 24 (median 3). Over time, the complication rate tended to decrease (from 16 to 10%, P = .07). Complication rate was not related to a diagnosis of congenital heart disease, age, or implant volume.
ICD use increased dramatically in children from 1997 to 2006, although implantation declined in patients with a concomitant diagnosis of life-threatening arrhythmia (those likely to undergo implantation for secondary prevention). The complication rate tended to decrease overall. Each center implants relatively few ICDs per year, which may have implications for competency and training.
植入式心脏复律除颤器(ICD)在儿童中的适应证已经扩大,但缺乏儿科人群的 ICD 植入数据。
我们描述了 1997 年至 2006 年美国儿童 ICD 使用的趋势。
我们分析了 1997 年、2000 年、2003 年和 2006 年儿童住院数据库(KID)中年龄小于 18 岁的患者的 ICD 植入的全国性医院管理数据,并对患者、医院和住院相关结局进行了特征描述。
每年儿童 ICD 植入数量增加了 3 倍(从 1997 年的 130 例增加到 2006 年的 396 例,P =.003)。同时伴有威胁生命的心律失常诊断的植入比例从 77%下降至 45%(P =.001)。患者的平均年龄从 13.6 岁下降至 12.2 岁(P =.01),小于 5 岁的患者比例也呈上升趋势(最高达到 10%,P =.09)。2006 年,每个中心的植入数量从 1 例到 24 例不等(中位数为 3 例)。随着时间的推移,并发症发生率呈下降趋势(从 16%降至 10%,P =.07)。并发症发生率与先天性心脏病诊断、年龄或植入物数量无关。
1997 年至 2006 年,儿童 ICD 的使用量大幅增加,尽管同时伴有威胁生命的心律失常诊断的患者(可能因二级预防而接受植入治疗)的植入数量有所下降。总体而言,并发症发生率呈下降趋势。每个中心每年植入的 ICD 数量相对较少,这可能对医生的技术水平和培训水平有影响。