de Groen Piet C
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.
Gastrointest Endosc Clin N Am. 2010 Oct;20(4):699-716. doi: 10.1016/j.giec.2010.07.012.
Colorectal cancer is the second major cause of cancer-related death in the United States. The long time involved in progression of mucosal dysplasia from a small polyp to an invasive cancer and the ability to image the colon mucosa are features that make early detection and prevention of colorectal cancer by colonoscopy possible. Although colonoscopy has contributed to a marked decline in the number of colorectal cancer-related deaths, the protective effect of colonoscopy, when used in routine clinical practice, has not lived up to the expectations raised by carefully controlled prospective research studies. Therefore new systems that assess quality of colonoscopy are needed.
结直肠癌是美国癌症相关死亡的第二大主要原因。从一个小息肉发展为浸润性癌的黏膜发育异常过程耗时较长,以及对结肠黏膜进行成像的能力,这些特点使得通过结肠镜检查早期发现和预防结直肠癌成为可能。尽管结肠镜检查已使结直肠癌相关死亡人数显著下降,但在常规临床实践中使用时,结肠镜检查的保护作用并未达到精心控制的前瞻性研究提出的预期。因此,需要新的系统来评估结肠镜检查的质量。