Department of Pediatrics, Sir Padampat Mother and Child Health Institute, SMS Medical College, Jaipur, Rajasthan, India.
Indian J Pediatr. 2010 Oct;77(10):1103-7. doi: 10.1007/s12098-010-0202-2. Epub 2010 Oct 2.
To study the clinico-epidemiological profile of children hospitalized with dengue illness.
Prospective study of children hospitalized with the diagnosis of dengue illness during from September through November 2006 at a tertiary care centre in Jaipur.
A total of 948 children including 671 (70.8%) boys and 277 (29.2%) girls were diagnosed to have dengue illness during the outbreak. Two third of children were from urban areas while 6-12 years was the most commonly affected age group (45.8%). 58.3% cases had dengue fever (DF) while 41.7% had DHF (dengue hemorrhagic fever). Dengue fever with bleed (DFB) accounted for 32% of cases. Common constitutional symptoms were vomiting (35.2%), pain abdomen (22.1%) and myalgia (10.1%). Bleeding manifestations were observed in 44.5% of cases.. Positive tourniquet test was the most common manifestation which was seen in 300 cases (31.6%) while in 9.2% cases bleeding was the only manifestation. Epistaxis (25%) was the most common spontaneous bleeding manifestation. Thrombocytopenia was documented in 84% of total cases and bleeding occurred more often in patients with severe thrombocytopenia. Ten children expired with a case fatality rate of 1.1%.
Children between 6 and 12 yrs were most affected by dengue with larger number of cases from urban areas. DFB cases accounted for almost one third cases of dengue. Epistaxis was the most common spontaneous bleeding manifestation. Bleeding occurs more often in patients with severe thrombocytopenia.
研究登革热患儿的临床流行病学特征。
对 2006 年 9 月至 11 月在斋浦尔的一家三级护理中心住院的登革热患儿进行前瞻性研究。
共有 948 名儿童被诊断患有登革热，其中 671 名（70.8%）为男孩，277 名（29.2%）为女孩。三分之二的儿童来自城市地区，而 6-12 岁是最常见的受影响年龄组（45.8%）。58.3%的病例为登革热（DF），41.7%为登革出血热（DHF）。登革热伴出血（DFB）占病例的 32%。常见的全身症状有呕吐（35.2%）、腹痛（22.1%）和肌痛（10.1%）。44.5%的病例出现出血表现。阳性束臂试验是最常见的表现，见于 300 例（31.6%），而 9.2%的病例出血是唯一的表现。鼻出血（25%）是最常见的自发性出血表现。84%的病例血小板减少，血小板减少症越严重，出血越常见。有 10 例患儿死亡，病死率为 1.1%。
6-12 岁儿童受登革热影响最大，城市地区的病例较多。DFB 病例占登革热病例的近三分之一。鼻出血是最常见的自发性出血表现。血小板减少症越严重，出血越常见。
