Antitumor agents, 118. The isolation and characterization of bruceanic acid A, its methyl ester, and the new bruceanic acids B, C, and D, from Brucea antidysenterica.
作者信息
Toyota T, Fukamiya N, Okano M, Tagahara K, Chang J J, Lee K H
机构信息
Faculty of Integrated Arts and Sciences, Hiroshima University, Japan.
出版信息
J Nat Prod. 1990 Nov-Dec;53(6):1526-32. doi: 10.1021/np50072a020.
PMID:2089121
Abstract
The known bruceanic acid A [1] and its methyl ester 2, as well as the new bruceanic acids B [3], C [4], and D [5], have been isolated from Brucea antidysenterica. The structures of 1-5 were elucidated by spectral data. Compound 1 demonstrated cytotoxicity against KB and TE671 tumor cells. Compound 5 was cytotoxic against P-388 lymphocytic leukemia cells.
摘要
Zotero 插件