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[从不同诊所的各种标本和患者中分离出的金黄色葡萄球菌菌株对阿莫西林克拉维酸钾(及其他抗生素)敏感性的差异]

[Differences in sensitivity to Augmentin (and other antibiotics) of Staphylococcus aureus strains isolated from various specimens and patients from different clinics].

作者信息

Ruczkowska J, Dolna I

机构信息

Katedry i Zakładu Mikrobiologii Lek. AM we Wrocławiu.

出版信息

Przegl Lek. 1990;47(10):702-5.

PMID:2089448
Abstract

Susceptibility of 327 S. aureus strains isolated in 1988 from various materials obtained from patients hospitalized in various hospitals of Wrocław city has been studied. Antibiograms were made by the use of diffusion-disc method for 21 antibiotics, including augmentin. Penicillin and oxytetracycline showed weak action on the strains studies; percentage of sensitive strains was 8.6% and 27.6%, respectively. Efficacious effects, more than 90% of strains, showed vancomycin, rifampicin, netilmicin, cefamandole++, amikacin and cefalotin. Susceptibility for augmentin was equal to 89.3%, and for other 12 antibiotics 50 to 89%. Multiresistant strains presented 19.6% of all specimen studied: large percentage of that strains was isolated from Department of Anesthesiology and Intensive Therapy (56.8%) and pediatry departments (26.4%). Most frequently they occur in the urine (33.3%). They showed high susceptibility to vancomycin (100%), rifampicin (98.4%), netilmicin (93.8%) and cefamandole++ (85.9%). Susceptibility to augmentin was 54.7%.

摘要

对1988年从弗罗茨瓦夫市各医院住院患者获取的各种材料中分离出的327株金黄色葡萄球菌菌株的药敏性进行了研究。采用扩散纸片法对包括阿莫西林克拉维酸钾在内的21种抗生素进行了药敏试验。青霉素和土霉素对所研究的菌株作用较弱;敏感菌株的百分比分别为8.6%和27.6%。万古霉素、利福平、奈替米星、头孢孟多++、阿米卡星和头孢噻吩显示出高效,对90%以上的菌株有效。阿莫西林克拉维酸钾的药敏率为89.3%,其他12种抗生素的药敏率为50%至89%。多重耐药菌株占所有研究标本的19.6%:其中很大一部分菌株分离自麻醉学与重症治疗科(56.8%)和儿科(26.4%)。它们最常出现在尿液中(33.3%)。它们对万古霉素(100%)、利福平(98.4%)、奈替米星(93.8%)和头孢孟多++(85.9%)显示出高敏感性。对阿莫西林克拉维酸钾的药敏率为54.7%。

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