Verstraeten A A, van Nie R
Int J Cancer. 1978 Apr 15;21(4):473-5. doi: 10.1002/ijc.2910210412.
MTV antigens were demonstrable by radioimmunoassay in milk samples from individual DBAf mice, and in samples from (male BALB/c X female DBAf) F1 mice. Although some samples collected during the first lactation periods of these mice were virus-negative, all samples of later lactation periods were virus-positive. From 75 mice of the [ male BALB/c X female (male BALB/c X female DBAf)]Bc I population, milk samples were collected during one or more lactation periods and tested for the presence of viral antigens; the samples of 42 mice were virus-positive. In the ([BALB/c X (BALB/c X DBAf)] X BALB/c)Bc II population two groups were distinguished. In the first group, the progeny of virus-positive Bc I mothers, 37 out of 62 mice had detectable levels of viral antigen in the milk. None of the 43 samples from mice of the second group, derived from MTV-negative Bc I females, were virus-positive. These data suggest that the presence of viral antigens in the milk of DBAf mice is controlled by a single dominant gene; evidence for linkage of this gene and the albino locus was obtained (recombination percentage: 20).
通过放射免疫测定法在个别DBAf小鼠的乳汁样本以及（雄性BALB/c×雌性DBAf）F1小鼠的样本中检测到MTV抗原。尽管在这些小鼠首次泌乳期收集的一些样本病毒呈阴性，但后期泌乳期的所有样本病毒均呈阳性。从[雄性BALB/c×雌性（雄性BALB/c×雌性DBAf）]Bc I群体的75只小鼠中，在一个或多个泌乳期收集乳汁样本并检测病毒抗原的存在；42只小鼠的样本病毒呈阳性。在（[BALB/c×（BALB/c×DBAf）]×BALB/c）Bc II群体中区分出两组。在第一组中，病毒呈阳性的Bc I代母鼠的后代，62只小鼠中有37只在乳汁中检测到可检测水平的病毒抗原。来自第二组小鼠的43个样本均来自MTV呈阴性的Bc I代雌性小鼠，均未呈病毒阳性。这些数据表明，DBAf小鼠乳汁中病毒抗原的存在受单个显性基因控制；获得了该基因与白化病基因座连锁的证据（重组率：20）。
