Roszkowski W, Roszkowski K, Ko H L, Beuth J, Jeljaszewicz J
National Institute of Tuberculosis and Lung Diseases, Warszawa, Poland.
Zentralbl Bakteriol. 1990 Dec;274(3):289-98. doi: 10.1016/s0934-8840(11)80686-9.
The ability of bacteria and bacterial products to modulate the immune response to unrelated antigens is well documented. Propionibacteria are amongst the most potent immunomodulators stimulating cell populations involved in nonspecific resistance. Generally, the activated immune system provides protection from infectious pathogens and malignancies via mechanisms of recognition and elimination. Accordingly, administration of propionibacteria could be shown to be of benefit in the treatment of neoplastic and infectious diseases. Thus, it can be recommended for further clinical investigations.
细菌及其产物调节对无关抗原免疫反应的能力已有充分文献记载。丙酸杆菌是最有效的免疫调节剂之一，可刺激参与非特异性抵抗的细胞群体。一般来说，激活的免疫系统通过识别和清除机制来抵御感染性病原体和恶性肿瘤。因此，已证明施用丙酸杆菌对治疗肿瘤和感染性疾病有益。因此，建议进一步进行临床研究。
