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[通过免疫荧光和补体结合试验测定的针对沙眼衣原体抗体滴度演变的特异性治疗效果]

[Effect of specific treatment on the evolution of antibody titers against Chlamydia trachomatis measured by the immunofluorescence and complement fixation tests].

作者信息

Cañada J L, Urkiola M A, Cisterna J R

机构信息

Departamento de Microbiologia e Inmunologia, Universidad del Pais Vasco (EHU), Bilbao.

出版信息

Enferm Infecc Microbiol Clin. 1990 Apr;8(4):228-30.

PMID:2090210
Abstract

We have evaluated the results of a serologic study of 34 patients with a possible chlamydial infection, obtaining three successive serum samples that were assessed with microimmunofluorescence (IIF) and complement fixation (CF) tests, so as to establish a comparison between the antibody titer measured by each of them. CF detects antibodies against the genus antigen, whereas IIF detects antibodies against the type-specific antigen. The antibodies against both antigens decrease in a parallel fashion, although somewhat more slowly in those against group antigen. This difference is significant (p less than 0.05).

摘要

我们评估了34例可能感染衣原体患者的血清学研究结果，获取了连续三份血清样本，并用微量免疫荧光法（IIF）和补体结合试验（CF）进行检测，以比较两种检测方法测得的抗体滴度。CF检测针对属抗原的抗体，而IIF检测针对型特异性抗原的抗体。针对这两种抗原的抗体呈平行下降趋势，不过针对群抗原的抗体下降速度稍慢。这种差异具有统计学意义（p小于0.05）。

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