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体外冲击波碎石术治疗老年人:年龄和合并症对结石清除率和并发症的影响。

Extracorporeal shockwave lithotripsy in elderly: impact of age and comorbidity on stone-free rate and complications.

机构信息

Department of Urology, University Hospital Osijek, The Reference Center for Urolythiasis of Croatian Ministry of Health, Osijek, Croatia.

出版信息

J Endourol. 2010 Nov;24(11):1831-7. doi: 10.1089/end.2009.0329. Epub 2010 Oct 4.

Abstract

INTRODUCTION

The aim of this study was to investigate and compare the success and complication rates of extracorporeal shockwave lithotripsy (SWL) in three cohorts of patients older than 60 years.

PATIENTS AND METHODS

Our study included 444 patients older than 60 years who were treated with SWL between May 2001 and May 2008 at the Croatian Referential Center for Urolythiasis in Osijek. Three groups were formed: group I (60-65 years old), group II (66-70), and group III (> 70). There were 175, 151, and 118 patients in groups I, II, and III, respectively, with a mean age of 67.7 ± 5.4 years for all patients. Demographic data, comorbidities, kidney function, stone characteristics, treatment details, complications, and stone-free rate (SFR) were analyzed.

RESULTS

We performed 1.7 ± 1.12 sessions per patient, with 3166 ± 571.3 impulses per session and a mean energy of 18.78 ± 0.64 kV. Three groups did not differ in number of SWL sessions (p = 0.78), number of impulses (p = 0.34), energy level (p = 0.5), stone size (p = 0.3), and pretreatment creatinine level (p = 0.88). Comorbidities were found in 55% of patients, with almost every third patient having two or more ones present. Complications were noted in 6% of patients, with no significant difference when comparing complication rates between the groups. An overall SFR of 67.98% was found. There was no statistically significant difference when comparing SFRs between the studied groups, even after dividing patients into those with renal and ureteral stones.

CONCLUSION

Our study shows that good SFR and low rate of complications can be achieved with proper patient selection for SWL, regardless of patients' age and comorbidities.

摘要

介绍

本研究旨在调查和比较三组 60 岁以上患者行体外冲击波碎石术(SWL)的成功率和并发症发生率。

患者与方法

我们的研究纳入了 2001 年 5 月至 2008 年 5 月在奥西耶克克罗地亚尿路结石参考中心接受 SWL 治疗的 444 例 60 岁以上患者。将患者分为三组:I 组(60-65 岁)、II 组(66-70 岁)和 III 组(>70 岁)。I 组、II 组和 III 组分别有 175、151 和 118 例患者,所有患者的平均年龄为 67.7 ± 5.4 岁。分析了患者的人口统计学数据、合并症、肾功能、结石特征、治疗细节、并发症和结石清除率(SFR)。

结果

我们为每位患者进行了 1.7 ± 1.12 次 SWL 治疗,每次治疗的脉冲数为 3166 ± 571.3 个,平均能量为 18.78 ± 0.64 kV。三组患者的 SWL 治疗次数(p = 0.78)、脉冲数(p = 0.34)、能量水平(p = 0.5)、结石大小(p = 0.3)和治疗前肌酐水平(p = 0.88)均无差异。55%的患者存在合并症,几乎每 3 名患者就有 2 种或以上合并症。6%的患者出现了并发症,但组间并发症发生率无显著差异。总的 SFR 为 67.98%。即使将患者分为肾结石和输尿管结石组后,比较各组的 SFR 也无统计学差异。

结论

本研究表明,只要对 SWL 进行适当的患者选择,无论患者的年龄和合并症如何,都可以获得良好的 SFR 和较低的并发症发生率。

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