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2010 年流感季期间,西澳大利亚州孕妇对 2009 年甲型 H1N1 流感大流行疫苗的接种情况。

Pandemic (H1N1) 2009 influenza vaccine uptake in pregnant women entering the 2010 influenza season in Western Australia.

机构信息

Joondalup Health Campus, Joondalup, WA, Australia.

出版信息

Med J Aust. 2010 Oct 4;193(7):405-7. doi: 10.5694/j.1326-5377.2010.tb03970.x.

Abstract

OBJECTIVE

To audit the uptake of pandemic (H1N1) 2009 influenza vaccine in pregnant women entering the 2010 influenza season in Western Australia, and to identify why some women did not receive the vaccine.

DESIGN, SETTING AND PARTICIPANTS: Cross-sectional study of consecutive patients attending the Joondalup Health Campus public antenatal clinics in WA in January 2010.

INTERVENTION

Audit of uptake of the H1N1-specific vaccine.

MAIN OUTCOME MEASURES

Rate of H1N1-specific vaccination, and reasons for not being the vaccinated.

RESULTS

479 of 541 women who attended the clinics (88.5%) were included in the audit. Three women had been infected with pandemic influenza in the preceding influenza season, leaving 476 women who were eligible for vaccination in pregnancy. Of these 476 women, only 33(6.9%) had been vaccinated. Of the remaining 443 women who were eligible to receive the vaccine but had not been vaccinated, 63.9% had not been offered vaccination despite multiple visits to their general practitioners during pregnancy, 19.6% had been advised by their GPs against vaccination in pregnancy, and 61.6% stated that they would decline vaccination if offered because of safety concerns.

CONCLUSIONS

Uptake of H1N1-specific influenza vaccine in pregnant women was poor. Reasons for this relate both to vaccination not being offered to or actively sought by the women, as well as concerns - of both the women and their GPs - about vaccine safety in pregnancy. Uptake in this setting may improve if vaccination is offered through public antenatal clinics with concurrent safety education for obstetricians and vaccination providers.

摘要

目的

调查 2010 年流感季进入西澳的孕妇对大流行性(H1N1)2009 流感疫苗的接种情况,并确定部分孕妇未接种疫苗的原因。

设计、地点和参与者:2010 年 1 月在西澳乔达路普健康园区公立产前诊所对连续就诊的患者进行的横断面研究。

干预措施

H1N1 特异性疫苗接种情况审计。

主要观察指标

H1N1 特异性疫苗接种率,以及未接种疫苗的原因。

结果

479 名参加诊所的 541 名妇女(88.5%)被纳入审计。3 名妇女在之前的流感季感染了大流行性流感,留下 476 名在孕期有资格接种疫苗的妇女。在这 476 名妇女中,只有 33 名(6.9%)接种了疫苗。在其余 443 名有资格接种但未接种疫苗的妇女中,63.9%尽管在孕期多次就诊,但未被医生提供疫苗接种,19.6%被医生建议在孕期不接种疫苗,61.6%表示如果提供疫苗,她们会因安全问题而拒绝接种。

结论

孕妇接种 H1N1 特异性流感疫苗的情况不佳。造成这种情况的原因既有妇女未主动寻求或未获得疫苗接种,也有妇女及其医生对孕期疫苗安全性的担忧。如果通过公立产前诊所提供疫苗接种,并为产科医生和疫苗接种提供者提供安全性教育,这种情况下的疫苗接种率可能会提高。

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