土耳其东地中海城市卡赫拉曼马拉什的孕妇大流行性流感疫苗接种状况及其影响因素。
Status of pandemic influenza vaccination and factors affecting it in pregnant women in Kahramanmaras, an eastern Mediterranean city of Turkey.
机构信息
Department of Public Health, Medical Faculty, Kahramanmaras Sutcuimam University, Kahramanmaras, Turkey.
出版信息
PLoS One. 2010 Dec 1;5(12):e14177. doi: 10.1371/journal.pone.0014177.
BACKGROUND
Pregnant women are a target group for receipt of influenza vaccine because there appears to be an elevated mortality and morbidity rate associated with influenza virus infection in pregnant women. The goal of this study is to determine the factors affecting the decisions of pregnant women in Turkey to be vaccinated or not for 2009 H1N1 influenza.
METHODOLOGY
We enrolled 314 of 522 (60.2%) pregnant women who attended to the antenatal clinics of the Medical Faculty of Kahramanmaras Sutcuimam University's Department of Gynecology and Obstetrics between December 23, 2009, and February 1, 2010. We developed a 48-question survey which was completed in a face-to-face interview at the clinic with each pregnant woman.
PRINCIPAL FINDINGS
Of the 314 pregnant women, 27.4% were in the first trimester, 33.8% were in the second trimester, and 38.8% were in the third trimester. Twenty-eight pregnant women (8.9%) got vaccinated. Of all the women interviewed, 68.5% stated that they were comfortable with their decisions about the vaccine, 7.3% stated they were not comfortable, and 24.2% stated that they were hesitant about their decisions. The probability of receiving the 2009 H1N1 vaccine was 3.46 times higher among working women than housewives, 1.85 times higher among women who have a child than those who do not, and 1.29 times higher among women with a high-school education or higher than those with only a secondary-school education and below. Correct knowledge about the minimal risks associated with receipt of influenza vaccine were associated with a significant increase in the probability of receiving the 2009 H1N1 vaccine.
CONCLUSIONS/SIGNIFICANCE: The number of pregnant women in the study group who received the 2009 H1N1 vaccine was very low (8.9%) and two-thirds of them stated that they were comfortable with their decisions concerning the vaccine. Our results may have implications for public health measures to increase the currently low vaccination rate among pregnant women. Further studies are required to confirm whether our findings generalize to other influenza seasons and other settings.
背景
孕妇是接种流感疫苗的目标人群，因为孕妇感染流感病毒似乎会导致死亡率和发病率升高。本研究旨在确定影响土耳其孕妇对 2009 年 H1N1 流感疫苗接种决策的因素。
方法
我们招募了 2009 年 12 月 23 日至 2010 年 2 月 1 日期间在卡赫拉曼马拉斯苏特库伊马姆大学医学院妇产科产前门诊就诊的 522 名孕妇中的 314 名（60.2%）。我们设计了一个 48 个问题的调查问卷，每个孕妇在诊所进行面对面访谈时完成。
主要发现
在 314 名孕妇中，27.4%处于孕早期，33.8%处于孕中期，38.8%处于孕晚期。28 名孕妇（8.9%）接种了疫苗。在接受采访的所有女性中，68.5%表示对疫苗接种决定感到满意，7.3%表示不满意，24.2%表示犹豫不决。与家庭主妇相比，职业女性接种 2009 年 H1N1 疫苗的概率高 3.46 倍，有孩子的女性比没有孩子的女性高 1.85 倍，接受过高中及以上教育的女性比仅接受过中学及以下教育的女性高 1.29 倍。对流感疫苗相关最小风险的正确认识与接种 2009 年 H1N1 疫苗的概率显著增加有关。
结论/意义：研究组中接种 2009 年 H1N1 疫苗的孕妇人数非常低（8.9%），三分之二的孕妇表示对疫苗接种决定感到满意。我们的研究结果可能对提高孕妇目前较低的疫苗接种率的公共卫生措施有影响。需要进一步的研究来确认我们的发现是否适用于其他流感季节和其他环境。
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