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后路器械性融合与前路腰椎间融合术治疗成人低度峡部裂性脊柱滑脱的对比研究。

Comparison study of the instrumented circumferential fusion with instrumented anterior lumbar interbody fusion as a surgical procedure for adult low-grade isthmic spondylolisthesis.

机构信息

Department of Neurosurgery, Wooridul Spine Hospital, Seoul, Korea.

出版信息

World Neurosurg. 2010 May;73(5):565-71. doi: 10.1016/j.wneu.2010.02.057.

Abstract

BACKGROUND

Instrumented circumferential fusion has been used as a primary and salvage procedure in lumbar spine fusion, especially for adult low-grade isthmic spondylolisthesis. Recently, instrumented anterior lumbar interbody fusion (ALIF) has been shown to provide good clinical and radiologic results that are comparable with those attained with traditional lumbar fusion. However, there have been no reports available that compare instrumented circumferential fusion with instrumented ALIF.

METHODS

Between January 2003 and November 2004, a total of 43 consecutive patients underwent instrumented ALIF (group I) at one hospital of the authors. Between February 2003 and October 2006, a total of 32 consecutive patients underwent instrumented circumferential fusion (group II) at the other hospital of the authors. The authors retrospectively reviewed clinical and radiologic data from patients. The time spent on the operation, blood loss, blood transfusions, the length of hospital stay, complications, clinical results, and radiologic results, including disc height (DH), degree of listhesis, segmental lordosis (SL), and whole lumbar lordosis (WL), were analyzed and compared. Clinical outcomes were graded using visual analog scale (VAS) scores. Functional outcomes were measured using Oswestry Disability Index (ODI) scores and return-to-work status.

RESULTS

The mean follow-up period was 41.1 and 32.9 months in group I and group II, respectively. Radiologic evidence of fusion was noted in 42 of 43 patients in group I and in 32 of 32 patients in group II. In both groups, all of the radiologic data, including the DH, degree of listhesis, SL, and WL significantly changed from the preoperative to postoperative period except for WL in group II. In both groups, VAS scores for back and leg pain and ODI scores significantly changed from the preoperative to postoperative period. There was no significant difference for VAS scores for back ODI scores in the two treatment groups after surgery. The mean time until return to work was 3.7 months in group I and 3.6 months in group II (p < .05). The mean hospital stay for group I (7.4 days) was shorter than that for group II (15.2 days) (p < .05). The mean operation time in group I (190 minutes) was shorter than that in group II (260.8 minutes) (p < .05). The mean blood loss in group I (300 mL) was less than that in group II (379 mL) (p < .05).

CONCLUSIONS

According to the present clinical outcome, instrumented ALIF is at least as effective as instrumented circumferential fusion for the treatment of back pain in adult patients with low-grade isthmic spondylolisthesis. Moreover, in terms of operative data including the duration of operation and hospital stay, as well as blood loss, instrumented ALIF demonstrates better results.

摘要

背景

在腰椎融合术中,器械性环周融合已被用作主要和挽救性手术,特别是用于成人低度峡部裂性脊椎滑脱。最近,器械性前路腰椎椎间融合术(ALIF)已显示出良好的临床和影像学结果,与传统腰椎融合术相当。然而,目前还没有报告比较器械性环周融合与器械性 ALIF。

方法

2003 年 1 月至 2004 年 11 月,作者所在的一家医院共对 43 例连续患者进行了器械性 ALIF(I 组)。2003 年 2 月至 2006 年 10 月,作者所在的另一家医院共对 32 例连续患者进行了器械性环周融合(II 组)。作者回顾性分析了患者的临床和影像学数据。分析并比较了手术时间、失血量、输血、住院时间、并发症、临床结果和影像学结果,包括椎间盘高度(DH)、滑脱程度、节段前凸(SL)和整个腰椎前凸(WL)。临床结果采用视觉模拟评分(VAS)评分进行分级。功能结果采用 Oswestry 残疾指数(ODI)评分和恢复工作状态进行测量。

结果

I 组和 II 组的平均随访时间分别为 41.1 和 32.9 个月。I 组 43 例患者中,42 例有影像学融合证据,II 组 32 例患者中有 32 例有影像学融合证据。在两组中,DH、滑脱程度、SL 和 WL 等所有影像学数据均从术前到术后均有明显变化,除 II 组 WL 外。两组患者的腰痛和腿痛 VAS 评分以及 ODI 评分均从术前到术后均有明显变化。两组术后 VAS 腰痛评分和 ODI 评分无显著差异。I 组平均返回工作时间为 3.7 个月,II 组为 3.6 个月(p<0.05)。I 组的平均住院时间(7.4 天)短于 II 组(15.2 天)(p<0.05)。I 组的平均手术时间(190 分钟)短于 II 组(260.8 分钟)(p<0.05)。I 组的平均失血量(300 毫升)少于 II 组(379 毫升)(p<0.05)。

结论

根据目前的临床结果,器械性 ALIF 治疗成人低度峡部裂性脊椎滑脱引起的腰痛至少与器械性环周融合一样有效。此外,在手术时间、住院时间和失血量等手术数据方面,器械性 ALIF 显示出更好的结果。

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