Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada.
Ophthalmic Plast Reconstr Surg. 2011 May-Jun;27(3):e81-3. doi: 10.1097/IOP.0b013e3181eea809.
A 31-year-old woman underwent an evisceration of her blind, painful right eye with placement of an aluminum oxide orbital implant. Histopathologic assessment revealed functional hematopoietic bone marrow, confirmed by immunohistochemistry, within osseous metaplasia of the retinal pigment epithelium. This finding is exceedingly rare, with few cases reported in the English literature. This report raises numerous questions, including the association between pain and hematopoietic bone marrow formation, the potential benefits of hematopoietic bone marrow in the eye, and the molecular biologic basis for this rare phenomenon.
一位 31 岁女性因右眼失明且疼痛而行眼球剜除术，并植入了氧化铝眶内植入物。组织病理学评估显示，在视网膜色素上皮的骨质变性中有功能造血骨髓，免疫组织化学也证实了这一点。这种发现极为罕见，英文文献中报道的病例很少。本报告提出了许多问题，包括疼痛与造血骨髓形成之间的关联、造血骨髓在眼睛中的潜在益处，以及这种罕见现象的分子生物学基础。
