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免疫功能正常患者的荚膜组织胞浆菌人工瓣膜心内膜炎，真菌血培养和荚膜组织胞浆菌抗原检测均为阴性。

Histoplasma capsulatum prosthetic valve endocarditis with negative fungal blood cultures and negative histoplasma antigen assay in an immunocompetent patient.

机构信息

Division of Infectious Diseases and HIV Medicine, Department of Medicine, University Hospitals Case Medical Center and Case Western Reserve University, 11000 Euclid Avenue, Cleveland, OH 44106, USA.

出版信息

J Clin Microbiol. 2010 Dec;48(12):4664-6. doi: 10.1128/JCM.01390-10. Epub 2010 Oct 6.

DOI:10.1128/JCM.01390-10
PMID:20926709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3008473/
Abstract

We report a case of Histoplasma capsulatum endocarditis in which Histoplasma antigen assay and fungal blood cultures were negative. The diagnosis was made by microscopic examination and culture of the excised valve. Histoplasma capsulatum should be considered in the differential diagnosis of culture-negative endocarditis in regions where it is endemic and in travelers.

摘要

我们报告了一例荚膜组织胞浆菌心内膜炎病例，该病例的荚膜组织胞浆菌抗原检测和真菌血培养均为阴性。诊断是通过切除瓣膜的显微镜检查和培养得出的。在该疾病流行地区和旅行者中，对于培养阴性的心内膜炎，应考虑荚膜组织胞浆菌作为鉴别诊断。

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本文引用的文献

1
Comprehensive diagnostic strategy for blood culture-negative endocarditis: a prospective study of 819 new cases.血培养阴性心内膜炎的综合诊断策略：819 例新病例的前瞻性研究。
Clin Infect Dis. 2010 Jul 15;51(2):131-40. doi: 10.1086/653675.
2
Fungal prosthetic valve endocarditis: Mayo Clinic experience with a clinicopathological analysis.真菌性人工心脏瓣膜心内膜炎：梅奥诊所的临床病理分析经验。
Mycoses. 2011 Jul;54(4):354-60. doi: 10.1111/j.1439-0507.2010.01884.x. Epub 2010 Apr 6.
3
Dramatic reduction in infective endocarditis-related mortality with a management-based approach.采用基于管理的方法显著降低感染性心内膜炎相关死亡率。
Arch Intern Med. 2009 Jul 27;169(14):1290-8. doi: 10.1001/archinternmed.2009.192.
4
Detection of histoplasma antigen by a quantitative enzyme immunoassay.通过定量酶免疫测定法检测组织胞浆菌抗原。
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Clin Microbiol Rev. 2007 Jan;20(1):115-32. doi: 10.1128/CMR.00027-06.
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Arch Pathol Lab Med. 1994 Dec;118(12):1205-8.