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A simple and general platform for generating stereochemically complex polyene frameworks by iterative cross-coupling.

作者信息

Lee Suk Joong, Anderson Thomas M, Burke Martin D

机构信息

Howard Hughes Medical Institute, Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL 61801, USA.

出版信息

Angew Chem Int Ed Engl. 2010 Nov 15;49(47):8860-3. doi: 10.1002/anie.201004911.

DOI:10.1002/anie.201004911
PMID:20927795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3037596/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/5ea4eaedd694/anie0049-8860-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/050c7fe4465d/anie0049-8860-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/ed34ffe3a3a0/anie0049-8860-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/81e76ea48851/anie0049-8860-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/366c00ee0338/anie0049-8860-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/c5f6a2777ee5/anie0049-8860-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/a9d413f2e43c/anie0049-8860-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/5ea4eaedd694/anie0049-8860-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/050c7fe4465d/anie0049-8860-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/ed34ffe3a3a0/anie0049-8860-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/81e76ea48851/anie0049-8860-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/366c00ee0338/anie0049-8860-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/c5f6a2777ee5/anie0049-8860-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/a9d413f2e43c/anie0049-8860-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef0/3546372/5ea4eaedd694/anie0049-8860-f7.jpg

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Alkyne elementometalation-Pd-catalyzed cross-coupling. Toward synthesis of all conceivable types of acyclic alkenes in high yields, efficiently, selectively, economically, and safely: "green" way.
报道的新霉素 B 结构的全合成。
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