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新残疾亚型对中国老年人 3 年死亡率的影响。

Effect of new disability subtype on 3-year mortality in Chinese older adults.

机构信息

Division of Physical Therapy, Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina, USA.

出版信息

J Am Geriatr Soc. 2010 Oct;58(10):1952-8. doi: 10.1111/j.1532-5415.2010.03013.x.

Abstract

OBJECTIVES

To examine a new method of classifying disability subtypes by combining self-reported and performance-based tools to predict mortality in older Chinese adults.

DESIGN

Prospective cohort study.

SETTING

Community-dwelling older adults.

PARTICIPANTS

Sixteen thousand twenty Chinese adults aged 65 and older from the Chinese Longitudinal Healthy Longevity Survey (CLHLS).

MEASUREMENTS

Self-reported activities of daily living (ADLs) and physical performance (PP) tests (chair standing, lifting a book from floor, turning 360°) cross-classified to create mutually exclusive disability subtypes: subtype 0 (no limitations in PP or ADLs), subtype 1 (limitations in PP, no limitations in ADLs), subtype 2 (no limitations in PP, limitations in ADLs), and subtype 3 (limitations in PP and ADLs). Outcome was mortality over 3 years.

RESULTS

Cox proportional hazard models, controlling for sociodemographic variables, living situation, healthcare access, social support, health status, and life-style, showed that older adults without any limitations in ADLs or PP had significantly lower mortality risk than those with other disability subtypes and that there was a graded pattern of greater mortality according to subtype 1 (hazard ratio (HR)=1.31, 95% confidence interval (CI)=1.20-1.42), 2 (HR=1.39, 95% CI=1.23-1.59), and 3 (HR=1.88, 95% CI=1.72-2.05). When compared with the average survival curve in the cohort, subtypes of isolated performance deficits or self-reported disability did not substantially discriminate risks of death over 3 years.

CONCLUSION

Combined use of self-reported and PP tools is necessary when screening for mutually exclusive disability subtypes that confer significantly higher or lower mortality risks on a population of older adults.

摘要

目的

通过结合自我报告和基于表现的工具来分类残疾亚型,以预测中国老年成年人的死亡率。

设计

前瞻性队列研究。

地点

社区居住的老年人。

参与者

来自中国长寿纵向研究(CLHLS)的 16020 名年龄在 65 岁及以上的中国成年人。

测量

自我报告的日常生活活动(ADL)和身体表现(PP)测试(椅子站立、从地板上提起书、转 360°)交叉分类,创建相互排斥的残疾亚型:亚型 0(PP 或 ADL 无限制),亚型 1(PP 受限,ADL 无限制),亚型 2(PP 无限制,ADL 受限)和亚型 3(PP 和 ADL 受限)。结果是 3 年内的死亡率。

结果

Cox 比例风险模型,控制了社会人口统计学变量、生活状况、医疗保健获取、社会支持、健康状况和生活方式,显示 ADL 或 PP 无任何限制的老年人死亡率显著低于其他残疾亚型,且根据亚型 1(危险比(HR)=1.31,95%置信区间(CI)=1.20-1.42)、2(HR=1.39,95% CI=1.23-1.59)和 3(HR=1.88,95% CI=1.72-2.05),死亡率呈递增模式。与队列中的平均生存曲线相比,孤立的表现缺陷或自我报告的残疾亚型在 3 年内并没有显著区分死亡风险。

结论

在筛选具有显著较高或较低死亡率风险的相互排斥的残疾亚型时,自我报告和 PP 工具的联合使用是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c79/3385853/04254273ccbf/nihms222916f1.jpg

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