轻度认知障碍患者的生成效应。
The generation effect in patients with mild cognitive impairment.
机构信息
Department of Psychology, University of Oviedo, Spain.
出版信息
Am J Alzheimers Dis Other Demen. 2010 Nov;25(7):576-84. doi: 10.1177/1533317510382284.
The generation effect (GE) has been proven as an effective technique to improve learning and memory in healthy and clinical populations. However, it has not been found with meaningless materials such as pseudowords. Several hypotheses postulate the participation of semantic memory in the information-generating process. There is indeed a clear decrease in the effect in patients with serious semantic memory disorders, such as Alzheimer's disease (AD) but, if this is correct, other patients whose memory disorders are not so serious, such as mild cognitive impairment (MCI), should show GE to some extent. To test this hypothesis, we examined 54 participants (18 healthy adults, 18 patients with AD, and 18 with MCI) in a task involving reading and completion of phrases. Results show a decreased (although obvious) GE in patients with MCI. Likewise, results indicate that greater semantic damage will lead to poorer performance with less familiar stimuli or low-frequency words.
生成效应 (GE) 已被证明是一种有效提高健康人群和临床人群学习和记忆的技术。然而，它在无意义的材料（如伪词）中并未发现。一些假说假设语义记忆参与了信息生成过程。在阿尔茨海默病 (AD) 等严重语义记忆障碍的患者中，确实明显降低了该效应，但如果这是正确的，那么其他记忆障碍不太严重的患者，如轻度认知障碍 (MCI)，应该在某种程度上表现出 GE。为了验证这一假设，我们在一项涉及阅读和完成短语的任务中对 54 名参与者（18 名健康成年人、18 名 AD 患者和 18 名 MCI 患者）进行了测试。结果表明，MCI 患者的 GE 明显降低（尽管仍明显）。同样，结果表明，更大的语义损伤将导致对不熟悉的刺激或低频词的表现更差。
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