Doctor Tahera H, Trivedi Sangeeta S, Chudasama Rajesh K
Department of Pediatrics, Government Medical College, Surat, India.
Lung India. 2010 Jul;27(3):145-8. doi: 10.4103/0970-2113.68317.
To obtain reference values for FEV(1), FVC, FEV(1)% and PEFR among children aged 8-14 years in south Gujarat region of India.
This cross-sectional study was conducted among 655 normal healthy school children (408 boys and 247 girls) of Surat city aged 8 to 14 years studying in V to VII standard during November 2007 to April 2008. Height, weight, body surface area were measured. All included children were tested in a sitting position with the head straight after taking written consent from parents. Spirometry was done using the spirometer "Spirolab II" MIR 010. Spirometer used in the study facilitates the total valuation of lung function including forced vital capacity (FVC), forced expiratory volume in one second (FEV(1)), forced expiratory volume ratio in one second (FEV(1)%) and peak expiratory flow rate (PEFR).
FVC, FEV(1) and PEFR were found to be statistically significant in the study groups. For FVC and FEV(1), highest correlation was found with age in girls and height in boys. For FEV(1)%, significant negative correlation was found with age and height in both sexes, but positive correlation was found with surface area. Similarly, PEFR showed highest correlation with surface area in boys and girls.
Variables such as FVC, FEV(1) and PEFR show good positive correlation with height, age and body surface area in both sexes. There is a need to have regional values for the prediction of normal spirometric parameters in a country like India with considerable diversity.
获取印度古吉拉特邦南部地区8至14岁儿童的第一秒用力呼气容积(FEV(1))、用力肺活量(FVC)、第一秒用力呼气容积百分比(FEV(1)%)和呼气峰值流速(PEFR)的参考值。
本横断面研究于2007年11月至2008年4月在苏拉特市655名8至14岁、就读于五至七年级的正常健康学童(408名男孩和247名女孩)中进行。测量了身高、体重和体表面积。所有纳入的儿童在获得家长书面同意后,以坐姿、头部挺直接受测试。使用“ Spirolab II” MIR 010型肺功能仪进行肺功能测定。该研究中使用的肺功能仪有助于全面评估肺功能,包括用力肺活量(FVC)、第一秒用力呼气容积(FEV(1))、第一秒用力呼气容积比例(FEV(1)%)和呼气峰值流速(PEFR)。
研究组中FVC、FEV(1)和PEFR在统计学上具有显著意义。对于FVC和FEV(1),女孩中与年龄的相关性最高,男孩中与身高的相关性最高。对于FEV(1)%,男女两性与年龄和身高均呈显著负相关,但与体表面积呈正相关。同样,PEFR在男孩和女孩中与体表面积的相关性最高。
FVC、FEV(1)和PEFR等变量在男女两性中与身高、年龄和体表面积均呈现良好的正相关。在像印度这样具有相当多样性的国家,需要有区域参考值来预测正常的肺功能参数。