Department of Obstetrics, Gynaecology and Neonatology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, NSW 2006, Australia.
Contraception. 2010 Nov;82(5):396-403. doi: 10.1016/j.contraception.2010.05.005.
Non-contraceptive health benefits are now recognized as an important aspect of the overall impact of all hormonal contraceptives. The levonorgestrel-releasing intrauterine systems (LNG IUS) are particularly effective at producing a number of health benefits for women using the LNG IUS as a contraceptive (reduced menstrual bleeding; reduced dysmenorrhea and the potential for prevention of a number of gynecological conditions in the longer term, such as iron-deficiency anemia, endometrial hyperplasia, uterine fibroids, acute episodes of pelvic inflammatory disease, endometriosis and perhaps others). The LNG IUS also has the potential to specifically treat a range of pre-existing gynecological conditions such as heavy menstrual bleeding due to a wide range of underlying causes, endometrial hyperplasia, uterine fibroids, adenomyosis, and endometriosis. These health benefits should be recognized as a key component in the decision-making process for individual women in choosing a specific type of hormonal or other contraceptive. Investment in research into the very substantial health benefits of hormonal contraceptives, such as the LNG IUS, has generally been ignored in comparison with the massive investment into understanding the often subtle or rare complications of hormonal contraceptive use. Both are important, but there is a real need to define more accurately those women who will benefit most from these health benefits.
非避孕健康益处现已被视为所有激素避孕方法整体影响的一个重要方面。左炔诺孕酮宫内节育系统（LNG IUS）在为使用 LNG IUS 作为避孕方法的女性带来多种健康益处方面特别有效（减少月经出血；减轻痛经，并且从长期来看可能预防一些妇科疾病，如缺铁性贫血、子宫内膜增生、子宫肌瘤、盆腔炎急性发作、子宫内膜异位症等）。LNG IUS 还有可能专门治疗一系列现有的妇科疾病，如由多种潜在病因引起的月经过多、子宫内膜增生、子宫肌瘤、子宫腺肌病和子宫内膜异位症。这些健康益处应该被视为女性在选择特定类型的激素或其他避孕方法时做出决策的关键因素。与大量投资于了解激素避孕使用中常见或罕见的副作用相比，对激素避孕药具（如 LNG IUS）的大量健康益处的研究投资通常被忽视。这两者都很重要，但确实需要更准确地确定那些最能从这些健康益处中受益的女性。
