Total France, Research Center of Gonfreville, 76700 Harfleur, France.
J Chromatogr A. 2011 May 27;1218(21):3146-52. doi: 10.1016/j.chroma.2010.08.082. Epub 2010 Sep 9.
The modulator is the key point of comprehensive two-dimensional gas chromatography (GC×GC). This interface ensures the sampling and transfer of the sample from the first to the second dimension. Many systems based on different principles have been developed. However, to our knowledge, almost only cryogenic modulators are used in the petroleum industry. Nevertheless cryogenic fluids represent some disadvantages in term of safety, cost and time consuming. This paper reports a comparative study between differential flow and cryogenic liquid modulators for the detailed analysis of hydrocarbons in middle distillates type light cycle oil (LCO). Optimization of geometrical dimensions of a set of columns was carried out on the differential flow modulator system in order to reproduce the quality of separation of cryogenic modulation. Then a comparative study was investigated on sensibility and resolution (separation space and peak capacity) between the two systems.
调制器是全二维气相色谱（GC×GC）的关键点。该接口确保了样品从第一维到第二维的采样和传输。已经开发出许多基于不同原理的系统。然而，据我们所知，几乎只有低温调制器在石油工业中使用。然而，低温流体在安全性、成本和耗时方面存在一些缺点。本文报道了一种差分流量和低温液体调制器的比较研究，用于中间馏分轻质循环油（LCO）中烃类的详细分析。在差分流量调制器系统上对一组柱子的几何尺寸进行了优化，以再现低温调制的分离质量。然后研究了两个系统在灵敏度和分辨率（分离空间和峰容量）之间的比较。
